Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16115770 | 0.87 | MRGPRX4 (0.47) | KMT2AMEN1BRD4MAOBNR4A2 | |
| SCHEMBL16137688 | 0.83 | KMT2A (0.40) | KMT2AMEN1BRD4MAOBNR4A2 | |
| SCHEMBL18725172 | 0.83 | KMT2A (0.40) | KMT2AMEN1BRD4MAOBNR4A2 | |
| SCHEMBL1172003 | 0.79 | MRGPRX4 (0.54) | MAOBNR4A2MRGPRX4SRD5A2 | |
| SCHEMBL8306162 | 0.76 | MEN1 (0.79) | KMT2AMEN1MAOBNR4A2PTGER1 | |
| SCHEMBL7809050 | 0.74 | KMT2A (0.57) | KMT2AMEN1MAOBNR4A2 | |
| SCHEMBL16115550 | 0.74 | KMT2A (0.60) | KMT2AMEN1MAOBNR4A2PTGER1 | |
| SCHEMBL13590516 | 0.74 | PLA2G4B (0.49) | KMT2AMEN1BRD4MAOBNR4A2 | |
| SCHEMBL16137686 | 0.73 | KMT2A (0.59) | KMT2AMEN1MAOBNR4A2PTGER1 | |
| SCHEMBL16115402 | 0.71 | BRD4 (0.43) | BRD4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |
| WO-2014154727-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |