Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 4/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 2/20 | 1.00 |
| ▸ | HSD17B2 | P37059 | 2/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 2/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoliquiritigenin SCHEMBL29522737 | 1.00 | CYP3A4 (1.00) | CYP3A4MEN1KMT2AMAPTHPGD | |
| Isoliquiritigenin SCHEMBL30383629 | 1.00 | CYP3A4 (1.00) | CYP3A4MEN1KMT2AMAPTHPGD | |
| Isoliquiritigenin SCHEMBL29396382 | 1.00 | CYP3A4 (1.00) | CYP3A4MEN1KMT2AMAPTHPGD | |
| Isoliquiritigenin SCHEMBL161169 | 1.00 | CYP3A4 (1.00) | CYP3A4MEN1KMT2AMAPTHPGD | |
| Isoliquiritigenin SCHEMBL10408923 | 1.00 | CYP3A4 (1.00) | CYP3A4MEN1KMT2AMAPTHPGD | |
| Isoliquiritigenin SCHEMBL25206430 | 0.98 | CYP3A4 (0.97) | CYP3A4MEN1KMT2AMAPTHPGD | |
| SCHEMBL25208375 | 0.98 | MEN1 (0.96) | CYP3A4MEN1KMT2AMAPTHPGD | |
| SCHEMBL25188827 | 0.92 | CYP3A4 (0.84) | CYP3A4MEN1KMT2AMAPTHPGD | |
| SCHEMBL28084572 | 0.92 | CYP3A4 (0.84) | CYP3A4MEN1KMT2AMAPTHPGD | |
| SCHEMBL23303982 | 0.90 | CYP3A4 (0.82) | CYP3A4MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5915 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122084804-A | Method for detecting contents of multi-index components of cough syrup oral liquid | — | 2026-05-26 | — | — | CN | claimed |
| CN-122070916-A | Application of arteannuin with double functions in promoting liver cell maturation and relieving liver lipid metabolism dysfunction | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2026-05-22 | — | — | CN | claimed |
| EP-4743565-A2 | CYTOKINE ENCODING LENTIVIRAL VECTORS AND USES THEREOF FOR MAKING TUMOR INFILTRATING LYMPHOCYTES | Iovance Biotherapeutics, Inc. (US) | 2026-05-20 | — | — | EP | claimed |
| CN-122031439-A | Application of isoliquiritigenin and/or glabridin in preparation of medicine for treating acanthamoeba infection | 上海市重大传染病和生物安全研究院 | 2026-05-15 | — | — | CN | claimed |
| CN-122005514-A | Application of isoliquiritigenin in preparation of medicines for treating 5-FU induced cardiotoxicity | 石河子大学 | 2026-05-12 | — | — | CN | claimed |
| CN-122005513-A | Anti-tumor and/or anti-iron death small molecule composition and application thereof | 北京慧宝源生物技术股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122005744-A | Quality marker for preventing and treating kidney-yang deficiency by using medicinal and edible formula composition, and preparation method and application thereof | 广西壮族自治区中医药研究院 | 2026-05-12 | — | — | CN | claimed |
| CN-121518510-B | Chalcone isopentenyl transferase gene GiPT, giPT protein, amplification primer set and application | 中国中医科学院中药研究所 | 2026-05-12 | — | — | CN | claimed |
| EP-3713561-B1 | COMBINATION OF BUTEIN, ISOLIQUIRITIGENIN AND SULFURETIN, AND ITS USE FOR THE TREATMENT OF DIABETES AND ASSOCIATED DISORDERS | OTAGO INNOVATION LTD (NZ) | 2026-05-06 | — | — | EP | claimed |
| US-20260108548-A1 | COMPOSITION OF PAEONIFLORIN AND ISOLIQUIRITIGENIN AND USE THEREOF | HENAN UNIVERSITY OF CHINESE MEDICINE (CN) | 2026-04-23 | — | — | US | claimed |
| WO-1993001824-A1 | COMBINATION THERAPY USING BIOFLAVONOID COMPOUNDS WITH ANTI-CANCER DRUGS | BAYLOR COLLEGE OF MEDICINE (US) | 1993-02-04 | — | — | WO | claimed |
| EP-0259499-B1 | ANTI-ALLERGIC AGENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-06-17 | — | — | EP | claimed |
| WO-1991017749-A1 | GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES | BAYLOR COLLEGE OF MEDICINE (US) | 1991-11-28 | — | — | WO | claimed |
| EP-0270690-B1 | DRUG FOR TREATMENT AND PROPHYLAXIS OF KIDNEY AND LIVER DISEASES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1991-05-15 | — | — | EP | claimed |
| US-4952564-A | ADMINISTERING ISOLIQUIRITIGENIN | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-08-28 | — | — | US | claimed |
| US-4898890-A | ADMINISTERING ISOLIQUIRITIGENIN | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1990-02-06 | — | — | US | claimed |
| EP-0292576-A1 | ANTI-ULCEROUS AGENT CONTAINING CHALCONE DERIVATIVE AS EFFECTIVE INGREDIENT AND NOVEL CHALCONE DERIVATIVES | TSUMURA & CO. (JP) | 1988-11-30 | — | — | EP | claimed |
| EP-0270690-A1 | DRUG FOR TREATMENT AND PROPHYLAXIS OF KIDNEY AND LIVER DISEASES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1988-06-15 | — | — | EP | claimed |
| EP-0259499-A1 | ANTI-ALLERGIC AGENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1988-03-16 | — | — | EP | claimed |
| EP-0257887-A2 | Ophthalmic compositions | HOUSTON BIOTECHNOLOGY INCORPORATED (US) | 1988-03-02 | — | — | EP | claimed |