SCHEMBL28084572

SCHEMBL28084572

O=C(O)C=Cc1ccc(C=CC(=O)c2ccc(O)cc2O)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.84
MEN1 O00255 5/20 0.84
KMT2A Q03164 5/20 0.84
MAPT P10636 4/20 0.84
HPGD P15428 4/20 0.84
ALOX15 P16050 4/20 0.84
MAPK1 P28482 4/20 0.84
NFKB1 P19838 3/20 0.84
HSD17B10 Q99714 3/20 0.84
TDP1 Q9NUW8 3/20 0.84
AKR1B1 P15121 3/20 0.84
TP53 P04637 3/20 0.84
CYP2C9 P11712 2/20 0.84
CYP2C19 P33261 2/20 0.84
HSD17B2 P37059 2/20 0.84
NFKB2 Q00653 2/20 0.84
RELA Q04206 2/20 0.84
LMNA P02545 2/20 0.84
CHRNA7 P36544 2/20 0.84
ESR1 P03372 2/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25188827 1.00 CYP3A4 (0.84) CYP3A4MEN1KMT2AMAPTHPGD
SCHEMBL25208375 0.93 MEN1 (0.96) CYP3A4MEN1KMT2AMAPTHPGD
Isoliquiritigenin SCHEMBL29396382 0.92 CYP3A4 (1.00) CYP3A4MEN1KMT2AMAPTHPGD
Isoliquiritigenin SCHEMBL30383629 0.92 CYP3A4 (1.00) CYP3A4MEN1KMT2AMAPTHPGD
Isoliquiritigenin SCHEMBL161168 0.92 CYP3A4 (1.00) CYP3A4MEN1KMT2AMAPTHPGD
Isoliquiritigenin SCHEMBL10408923 0.92 CYP3A4 (1.00) CYP3A4MEN1KMT2AMAPTHPGD
Isoliquiritigenin SCHEMBL161169 0.92 CYP3A4 (1.00) CYP3A4MEN1KMT2AMAPTHPGD
Isoliquiritigenin SCHEMBL29522737 0.92 CYP3A4 (1.00) CYP3A4MEN1KMT2AMAPTHPGD
Isoliquiritigenin SCHEMBL25206430 0.90 CYP3A4 (0.97) CYP3A4MEN1KMT2AMAPTHPGD
2',4'-Dihydroxychalcone SCHEMBL25200440 0.89 MAPT (1.00) CYP3A4MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105777536-A A novel bacteriostatic compound, a preparing method thereof and applications of the bacteriostatic compound in aquatic products 浙江海洋学院 2016-07-20 CN disclosed