SCHEMBL161170

SCHEMBL161170

O=C1OC2(c3ccc(O)cc3Oc3cc(O)c(Cl)c(Cl)c32)c2c(Cl)c(Cl)c(Cl)c(Cl)c21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMAD3 P84022 2/20 0.54
ALDH1A1 P00352 4/20 0.53
HPGD P15428 3/20 0.53
BRCA1 P38398 2/20 0.53
HSD17B10 Q99714 2/20 0.53
ALOX12 P18054 2/20 0.53
CYP2C9 P11712 1/20 0.53
ALOX15 P16050 1/20 0.53
FTO Q9C0B1 10/20 0.52
RECQL P46063 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPT P10636 3/20 0.52
BLM P54132 2/20 0.52
HTT P42858 2/20 0.52
CYP2C19 P33261 1/20 0.52
PRMT1 Q99873 1/20 0.52
ACE2 Q9BYF1 1/20 0.52
THRB P10828 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887310 0.90 ALDH1A1 (0.63) SMAD3ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL30887311 0.90 ALDH1A1 (0.63) SMAD3ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL134733 0.90 ALDH1A1 (0.63) SMAD3ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL29361906 0.90 ALDH1A1 (0.63) SMAD3ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL5453230 0.89 ALDH1A1 (0.62) SMAD3ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL6734651 0.89 ALDH1A1 (0.49) SMAD3ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL2318271 0.89 ALDH1A1 (0.47) SMAD3ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL7454803 0.88 ALDH1A1 (0.50) SMAD3ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL2316195 0.88 ALDH1A1 (0.48) SMAD3ALDH1A1HPGDBRCA1HSD17B10
SCHEMBL1463198 0.87 SMAD3 (0.56) SMAD3ALDH1A1HPGDBRCA1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4533 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121575125-A Primer probe set for identifying round-mouth copper fish and application 武汉大学 2026-02-27 CN claimed
US-12492437-B2 Compositions and methods for detecting or quantifying hepatitis C virus GEN-PROBE INCORPORATED (US) 2025-12-09 US claimed
WO-2025242900-A1 COACERVATE-FORMING REAGENTS AND METHODS PARTITIONBIO LTD (GB) 2025-11-27 WO claimed
EP-4647771-A1 ANTIBODY OR PEPTIDE BINDING SPECIFICALLY TO RNASE A, IMMUNOASSAY DEVICE AND METHOD FOR DETECTING RNASE A, AND METHOD FOR COLLECTING RNASE A UIF (University Industry Foundation), Yonsei University (KR) 2025-11-12 EP claimed
US-20250341517-A1 SWITCHING PEPTIDE, IMMUNOASSAY DEVICE COMPRISING SAME, AND IMMUNOASSAY METHOD USING SAME OPTOLANE TECH INC (KR) 2025-11-06 US claimed
US-20250340957-A1 Assays for the Detection of SARS-CoV2 Mutants PROCOMCURE BIOTECH GMBH (AT) 2025-11-06 US claimed
EP-4630559-A1 AFFINITY PROBES Qbiotix Limited (GB) 2025-10-15 EP claimed
US-12421560-B2 Assays for the detection of SARS-CoV-2 mutants PROCOMCURE BIOTECH GMBH (AT) 2025-09-23 US claimed
EP-4577858-A2 APPARATUS, SYSTEMS, AND METHODS FOR FLUORESCENCE IMAGING ON PLANAR SENSORS The Regents of University of California (US) 2025-07-02 EP claimed
CN-120193105-A Oligonucleotide probe of streptococcus thermophilus and preparation method and application thereof 中国计量科学研究院 2025-06-24 CN claimed
US-20030120063-A1 Method for deblocking of labeled oligonucleotides INVITROGEN CORPORATION 2003-06-26 US claimed
WO-2003030624-A2 HEPATITIS A VIRUS NUCLEOTIDE SEQUENCES, RECOMBINANT PROTEINS AND USES THEREOF CHIRON CORPORATION (US) 2003-04-17 WO claimed
WO-2003031934-A2 IDENTIFICATION OF OLIGONUCLEOTIDES FOR THE CAPTURE, DETECTION AND QUANTITATION OF HEPATITIS B VIRAL DNA CHIRON CORPORATION (US) 2003-04-17 WO claimed
EP-1185544-A4 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES INVITROGEN CORP (US) 2002-07-17 EP claimed
EP-1185544-A1 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES INVITROGEN CORPORATION (US) 2002-03-13 EP claimed
EP-1163368-A1 ENZYMATICALLY CATALYSED SIGNAL AMPLIFICATION Tepnel Medical Limited (GB) 2001-12-19 EP claimed
WO-2000071559-A9 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES INVITROGEN CORP (US) 2001-06-21 WO claimed
WO-2000071559-A1 METHOD FOR DEBLOCKING OF LABELED OLIGONUCLEOTIDES INVITROGEN CORPORATION (US) 2000-11-30 WO claimed
WO-2000055365-A1 ENZYMATICALLY CATALYSED SIGNAL AMPLIFICATION TEPNEL MEDICAL LIMITED (GB) 2000-09-21 WO claimed
US-6090543-A DETECTING THE PRESENCE OF A TARGET NUCLEIC ACID MOLECULE BY MIXING TOGETHER CLEAVAGE MEANS, TARGET NUCLEIC ACID, AND COMPLEMENTARY OLIGONUCLEOTIDES; THEN DETECTING NON-TARGET CLEAVAGE PRODUCTS THIRD WAVE TECHNOLOGIES, INC. (US) 2000-07-18 US claimed