Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316195 | 0.97 | ALDH1A1 (0.48) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL161170 | 0.89 | SMAD3 (0.54) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL6734651 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL30887310 | 0.80 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL29361906 | 0.80 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL30887311 | 0.80 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL134733 | 0.80 | ALDH1A1 (0.63) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL7454803 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL534888 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 | |
| SCHEMBL5453230 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HPGDBRCA1HSD17B10ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934374-B1 | NON-FLUORESCENT ENERGY TRANSFER | ROCHE DIAGNOSTICS GMBH (DE) | 2011-08-10 | — | — | EP | claimed |
| US-7741467-B2 | Non-fluorescent energy transfer | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2010-06-22 | — | — | US | claimed |
| EP-1934374-A2 | NON-FLUORESCENT ENERGY TRANSFER | Roche Diagnostics GmbH (DE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007039301-A2 | NON-FLUORESCENT ENERGY TRANSFER | ROCHE DIAGNOSTICS GMBH (DE) | 2007-04-12 | — | — | WO | claimed |
| US-20070077588-A1 | Non-fluorescent energy transfer | ROCHE MOLECULAR SYSTEMS, INC (US) | 2007-04-05 | — | — | US | claimed |
| EP-1934374-B1 | NON-FLUORESCENT ENERGY TRANSFER | ROCHE DIAGNOSTICS GMBH (DE) | 2011-08-10 | — | — | EP | disclosed |
| US-7741467-B2 | Non-fluorescent energy transfer | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2010-06-22 | — | — | US | disclosed |
| EP-1934374-A2 | NON-FLUORESCENT ENERGY TRANSFER | Roche Diagnostics GmbH (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007039301-A2 | NON-FLUORESCENT ENERGY TRANSFER | ROCHE DIAGNOSTICS GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |
| US-20070077588-A1 | Non-fluorescent energy transfer | ROCHE MOLECULAR SYSTEMS, INC (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070077588-A1 | Non-fluorescent energy transfer | DNTT, MTREX, GFPT1 | ALDH1A1 769/4885HPGD 800/4885BRCA1 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.