⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29145 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL28291843 | 0.73 | — | — | |
| Propane SCHEMBL28230936 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL263794 | 0.64 | — | — | |
| SCHEMBL15341 | 0.61 | — | — | |
| SCHEMBL4389530 | 0.61 | — | — | |
| SCHEMBL179958 | 0.60 | — | — | |
| SCHEMBL28019953 | 0.60 | — | — | |
| SCHEMBL2144119 | 0.60 | — | — | |
| SCHEMBL5005529 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492390-B2 | Synthesis of locked nucleic acid derivatives | SANTARIS PHARMA A/S (DK) | 2013-07-23 | — | — | US | disclosed |
| US-20120165514-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA A/S (DK) | 2012-06-28 | — | — | US | disclosed |
| US-8084458-B2 | Synthesis of locked nucleic acid derivatives | SANTARIS PHARMA A/S (DK) | 2011-12-27 | — | — | US | disclosed |
| US-20110087034-A1 | Organic Semiconductor Material | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-04-14 | — | — | US | disclosed |
| EP-2248818-A1 | ORGANIC SEMICONDUCTOR MATERIAL | Sumitomo Chemical Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100216983-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA A/S, a Denmark corporation | 2010-08-26 | — | — | US | disclosed |
| EP-0926154-B1 | NOVEL LACTOSAMINE OLIGOSACCHARIDES AND PROCESS FOR THE PREPARATION THEREOF | SEIKAGAKU KOGYO CO LTD (JP) | 2010-01-27 | — | — | EP | disclosed |
| US-7569575-B2 | Formed via intermediates which are reactive with nucleophiles | SANTARIS PHARMA A/S (DK) | 2009-08-04 | — | — | US | disclosed |
| EP-1501848-B1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA AS (DK) | 2007-08-08 | — | — | EP | disclosed |
| EP-1501848-A1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | Santaris Pharma A/S (DK) | 2005-02-02 | — | — | EP | disclosed |
| US-5498819-A | INHIBITORS OF PHOSPHODIESTERASE AS NEUROTROPIC AGENTS, ANTIINFLAMMATORY AGENTS, MUSCLE RELAXANTS, ANTICARCINOGENIC AGENTS AND ANTIDIABETIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0318060-B1 | Griseolic acid derivatives, their preparation and their use | SANKYO CO (JP) | 1995-10-25 | — | — | EP | disclosed |
| EP-0319050-B1 | Griseolic acid derivatives, their preparation and their use | SANKYO CO (JP) | 1995-04-12 | — | — | EP | disclosed |
| EP-0251827-B1 | NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0214708-B1 | GRISEOLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | SANKYO COMPANY LIMITED (JP) | 1989-12-13 | — | — | EP | disclosed |
| EP-0319050-A2 | Griseolic acid derivatives, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1989-06-07 | — | — | EP | disclosed |
| EP-0318060-A2 | Griseolic acid derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1989-05-31 | — | — | EP | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |