SCHEMBL29145

SCHEMBL29145

CC(C)(C)[Si](C)(C)[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28291843 0.95
Propane SCHEMBL28230936 0.88 TSHR (0.31)
SCHEMBL27374974 0.79 CA4 (0.30)
SCHEMBL1611767 0.76
SCHEMBL263794 0.67
SCHEMBL1988280 0.65
SCHEMBL15341 0.65
SCHEMBL4389530 0.65
SCHEMBL179958 0.63
SCHEMBL2144119 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6516 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853804-B Method for synthesizing high-regioselectivity alpha-alkenyl stannane by hydrogenating terminal alkyne stannum marshi 浙江大学 2024-07-05 CN claimed
CN-118234733-A Five-membered heterocyclic pyrimidine derivatives and application thereof as pan KRAS mutation inhibitor 思路迪生物医药(上海)有限公司 2024-06-21 CN claimed
CN-118215663-A Pyridopyrimidine derivatives serving as small GTPase KRAS mutation inhibitors 思路迪生物医药(上海)有限公司 2024-06-18 CN claimed
WO-2024111390-A1 COMPOUND AND METHOD FOR PRODUCING SAME 学校法人帝京大学 2024-05-30 WO claimed
EP-4373832-A1 PROCESSES OF MAKING ONAPRISTONE AND INTERMEDIATES THEREOF Context Biopharma Inc. (US) 2024-05-29 EP claimed
EP-4373827-A1 KRAS G12D INHIBITORS AND USES THEREOF Suzhou Zanrong Pharma Limited (CN) 2024-05-29 EP claimed
CN-112368292-B Phosphoramidite compound, preparation method and application thereof 深圳华大生命科学研究院 2024-05-17 CN claimed
EP-4367121-A1 COMPOUND OF THE 7A,8,9,10,11,11A-HEXAHYDRO-1H,7H-PYRANO[2,3-C]XANTHENE TYPE, METHOD OF PREPARATION THEREOF, INTERMEDIATES THEREOF AND THERAPEUTIC APPLICATIONS THEREOF Centre National de la Recherche Scientifique (FR) 2024-05-15 EP claimed
CN-117924393-A Monomer of 3' -mercapto nucleoside analogue and its synthesis process 天津兴博润生物制药有限公司 2024-04-26 CN claimed
US-20240132422-A1 Spin-Labeled Nucleosides and Phosphoramidites SOMALOGIC OPERATING CO., INC. (US) 2024-04-25 US claimed
US-4267117-A INTERMEDIATES FOR 1A-HYDROXYLATED CALCIFEROLS THE UPJOHN COMPANY (US) 1981-05-12 US claimed
EP-0019796-A1 Propionic acid esters, preparation of these compounds, herbicides containing these compounds as active substances, and the use of such compounds and agents for combating weeds F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-12-10 EP claimed
US-4213907-A Prostaglandin intermediates PFIZER INC. (US) 1980-07-22 US claimed
US-4206131-A 1A-HYDROXYLATED CALCIFEROLS THE UPJOHN COMPANY (US) 1980-06-03 US claimed
US-4183855-A INTERMEDIATES FOR PREPARATION OF THE BACTERICIDE, 1-OXADETHIA-CEPHALOSPORIN SHIONOGI & CO., LTD. (JP) 1980-01-15 US claimed
EP-0002590-A1 Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-06-27 EP claimed
US-4117014-A PROSTAGLANDIN DERIVATIVES ABBOTT LABORATORIES (US) 1978-09-26 US claimed
US-4091207-A Prostaglandin intermediate including oxathio heterocyclic ring PFIZER INC. (US) 1978-05-23 US claimed
US-4039563-A Process for preparing cyclopent-2-en-1-one derivatives TEIJIN LIMITED (JA) 1977-08-02 US claimed
US-4009196-A HYPOTENSIVE AGENTS, BRONCHODILATORS, PROSTAGLANDIN ANALOGS TEIJIN LIMITED (JA) 1977-02-22 US claimed