Known targets — ChEMBL curated mechanism
PDE10APDE1APDE1BPDE1CPDE2APDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE6APDE6BPDE6CPDE6DPDE6GPDE6HPDE7APDE7BPDE8APDE8BPDE9ASLC29A1
The experimentally established mechanism targets of Dipyridamole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 known ✓ | Q99808 | 19/20 | 1.00 |
| ▸ | PDE2A known ✓ | O00408 | 1/20 | 1.00 |
| ▸ | PDE6D known ✓ | O43924 | 1/20 | 1.00 |
| ▸ | PDE8A known ✓ | O60658 | 1/20 | 1.00 |
| ▸ | PDE5A known ✓ | O76074 | 1/20 | 1.00 |
| ▸ | PDE6A known ✓ | P16499 | 1/20 | 1.00 |
| ▸ | PDE6G known ✓ | P18545 | 1/20 | 1.00 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 1.00 |
| ▸ | PDE6B known ✓ | P35913 | 1/20 | 1.00 |
| ▸ | PDE6C known ✓ | P51160 | 1/20 | 1.00 |
| ▸ | PDE1A known ✓ | P54750 | 1/20 | 1.00 |
| ▸ | PDE1B known ✓ | Q01064 | 1/20 | 1.00 |
| ▸ | PDE4B known ✓ | Q07343 | 1/20 | 1.00 |
| ▸ | PDE4C known ✓ | Q08493 | 1/20 | 1.00 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 1.00 |
| ▸ | PDE3B known ✓ | Q13370 | 1/20 | 1.00 |
| ▸ | PDE7A known ✓ | Q13946 | 1/20 | 1.00 |
| ▸ | PDE6H known ✓ | Q13956 | 1/20 | 1.00 |
| ▸ | PDE1C known ✓ | Q14123 | 1/20 | 1.00 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridamole SCHEMBL3980595 | 1.00 | SLC29A1 (1.00) | SLC29A1ADORA3KDM4EMEN1PDE2A | |
| Dipyridamole SCHEMBL9743915 | 0.98 | SLC29A1 (0.97) | SLC29A1ADORA3KDM4EMEN1PDE2A | |
| Dipyridamole SCHEMBL7362290 | 0.98 | SLC29A1 (0.97) | SLC29A1ADORA3KDM4EMEN1PDE2A | |
| Dipyridamole SCHEMBL7998210 | 0.98 | SLC29A1 (0.97) | SLC29A1ADORA3KDM4EMEN1PDE2A | |
| Dipyridamole SCHEMBL17044166 | 0.97 | SLC29A1 (0.94) | SLC29A1ADORA3KDM4EMEN1PDE2A | |
| Dipyridamole SCHEMBL611283 | 0.95 | SLC29A1 (0.91) | SLC29A1ADORA3KDM4EMEN1PDE2A | |
| SCHEMBL17017272 | 0.93 | SLC29A1 (0.86) | SLC29A1ADORA3KDM4EMEN1PDE2A | |
| Dipyridamole SCHEMBL11234613 | 0.93 | SLC29A1 (0.86) | SLC29A1ADORA3KDM4EMEN1PDE2A | |
| SCHEMBL6915061 | 0.93 | SLC29A1 (0.86) | SLC29A1ADORA3KDM4EMEN1PDE2A | |
| SCHEMBL5055565 | 0.93 | SLC29A1 (0.86) | SLC29A1ADORA3KDM4EMEN1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 56971 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747263-A1 | LIPID NANOPARTICLES AND USES THEREOF | University of Connecticut (US) | 2026-05-27 | — | — | EP | claimed |
| WO-2026103722-A1 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF COAGULATION FACTOR XI (FXI) | SHANGHAI ARGO BIOPHARMACEUTICAL CO., LTD. (CN) | 2026-05-21 | — | — | WO | claimed |
| WO-2026098615-A1 | COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF IN PREPARATION OF DRUGS FOR TREATING CARDIOVASCULAR AND CEREBROVASCULAR DISEASES | 上海东西智荟生物医药有限公司 | 2026-05-15 | — | — | WO | claimed |
| US-20260124188-A1 | mGluR receptor antagonists for use in prevention andor treatment of bone marrow lesions (BML) andor osteoporosis, cartilage loss, osteosclerosis and osteitis in a mammal | ORPHELION AB (SE) | 2026-05-07 | — | — | US | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4724049-A1 | MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF | Catalent Ontario Limited (CA) | 2026-04-15 | — | — | EP | claimed |
| EP-4722725-A2 | COMPOSITIONS AND METHODS FOR EVALUATION OF ANTIPLATELET DRUG SENSITIVITY | Beth Israel Deaconess Medical Center, Inc. (US) | 2026-04-08 | — | — | EP | claimed |
| EP-4714452-A1 | METHODS FOR TREATING SARS COV-2 INFECTIONS | Gilead Sciences, Inc. (US) | 2026-03-25 | — | — | EP | claimed |
| US-20260076872-A1 | POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME | SIO2 MEDICAL PRODUCTS LLC (US) | 2026-03-19 | — | — | US | claimed |
| EP-4704971-A1 | GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY | Cognito Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | claimed |
| US-4367217-A | Dipyricamole sustained release forms comprising lacquer-coated particles and the preparation thereof | BOEHRINGER INGELHEIM GMBH (DE) | 1983-01-04 | — | — | US | claimed |
| US-4361546-A | SUSTAINED RELEASE OF DIPYRIDAMOLE | BOEHRINGER INGELHEIM GMBH (DE) | 1982-11-30 | — | — | US | claimed |
| US-4352789-A | COATING OF PERFLUORINATED SURFACTANT; INHALANTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-10-05 | — | — | US | claimed |
| US-4337254-A | ANTICOAGULANTS COMPRISING A PROSTACYCLIN AND A PHOSPHODIESTERASE INHIBITOR; PREVENTING LOWERING OF BLOOD PRESSURE | BURROUGHS WELLCOME CO. (US) | 1982-06-29 | — | — | US | claimed |
| EP-0036138-A2 | Composition of matter for topical application comprising a bio-affecting agent and N,N-diethyl-m-toluamide | MERCK & CO. INC. (US) | 1981-09-23 | — | — | EP | claimed |
| US-4248872-A | ADMINISTERING DIPYRIDAMOLE | ELECTION SYSTEMS & SOFTWARE, INC., F/K/A AMERICAN INFORMATION SYSTEMS, INC. | 1981-02-03 | — | — | US | claimed |
| EP-0011828-A1 | Pharmaceutical combinations including hydantoin derivatives, pharmaceutical formulations containing the combinations and methods of making the formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-06-11 | — | — | EP | claimed |
| US-4206214-A | Antithrombotic pharmaceutical compositions containing dipyridamole and sulfinpyrazone | BOEHRINGER INGELHEIM GMBH (DE) | 1980-06-03 | — | — | US | claimed |
| US-3992531-A | 2-Substituted adenosine-5'-carboxylates in the treatment of anginal pain | ABBOTT LABORATORIES (US) | 1976-11-16 | — | — | US | claimed |
| US-3962455-A | Antibiotic ascofuranone and process for the production thereof | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-06-08 | — | — | US | claimed |