Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1864641 | 0.89 | SMN1; SMN2 (0.46) | CREBBPLMNARAB9AMEN1TP53 | |
| SCHEMBL14098226 | 0.82 | CYP1A2 (0.65) | CREBBPLMNARAB9AMEN1TP53 | |
| SCHEMBL1867906 | 0.79 | CYP1A2 (0.43) | LMNARAB9AMEN1TP53MAPT | |
| SCHEMBL18579193 | 0.78 | RAB9A (0.72) | LMNARAB9AMEN1TP53MAPT | |
| SCHEMBL18256266 | 0.78 | TGM2 (0.59) | MEN1MAPTKMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL21894170 | 0.77 | TGM2 (0.58) | LMNARAB9AMEN1MAPTKMT2A | |
| SCHEMBL31162390 | 0.77 | TGM2 (0.58) | LMNARAB9AMEN1MAPTKMT2A | |
| SCHEMBL27616728 | 0.77 | TDP1 (0.51) | LMNAMEN1MAPTKMT2ATGM2 | |
| SCHEMBL14274490 | 0.76 | CYP1A2 (0.50) | LMNARAB9AMEN1TP53MAPT | |
| SCHEMBL3870279 | 0.75 | GAA (0.67) | RAB9AMEN1TP53MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014149164-A1 | MK2 INHIBITORS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |