Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611617 | 0.86 | TUBB1 (0.39) | TUBB1ALDH1A1PTGS1PTGS2ALOX5 | |
| SCHEMBL1610157 | 0.82 | TUBB1 (0.37) | TUBB1ALDH1A1PTGS1PTGS2ALOX5 | |
| SCHEMBL1609646 | 0.81 | CNR1 (0.37) | TUBB1ALDH1A1PTGS1PTGS2ALOX5 | |
| SCHEMBL9421133 | 0.79 | TUBB1 (0.46) | TUBB1ALDH1A1PTGS1PTGS2ALOX5 | |
| SCHEMBL5837450 | 0.79 | TUBB1 (0.46) | TUBB1ALDH1A1PTGS1PTGS2ALOX5 | |
| SCHEMBL27875847 | 0.79 | ALDH1A1 (0.40) | ALDH1A1PTGS1PTGS2ALOX5ALDH1A3 | |
| SCHEMBL1610718 | 0.79 | CNR1 (0.36) | TUBB1PTGS1PTGS2ALOX5TSHR | |
| SCHEMBL1611000 | 0.79 | CNR1 (0.36) | TUBB1PTGS1PTGS2ALOX5TSHR | |
| SCHEMBL16958501 | 0.78 | HTT (0.42) | TUBB1ALDH1A1PTGS1PTGS2ALOX5 | |
| Alcohol SCHEMBL28361987 | 0.78 | ALDH1A1 (0.44) | TUBB1ALDH1A1PTGS2ALDH1A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558574-A4 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO LTD (KR) | 2006-06-21 | — | — | EP | claimed |
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | DIGITAL BIOTECH CO., LTD. (KR) | 2005-12-29 | — | — | US | claimed |
| EP-1558574-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Digital Biotech Co., Ltd. (KR) | 2005-08-03 | — | — | EP | claimed |
| WO-2004035533-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO., LTD. (KR) | 2004-04-29 | — | — | WO | claimed |
| US-20110087034-A1 | Organic Semiconductor Material | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-04-14 | — | — | US | disclosed |
| EP-2248818-A1 | ORGANIC SEMICONDUCTOR MATERIAL | Sumitomo Chemical Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| EP-1558574-A4 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO LTD (KR) | 2006-06-21 | — | — | EP | disclosed |
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | DIGITAL BIOTECH CO., LTD. (KR) | 2005-12-29 | — | — | US | disclosed |
| EP-1558574-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Digital Biotech Co., Ltd. (KR) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004035533-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO., LTD. (KR) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | HRH2, HRH4, NMUR2 | TUBB1 3707/4885ALDH1A1 1397/4885PTGS1 67/4885 |
| US-20110087034-A1 | Organic Semiconductor Material | OR10J3, TST, OR51E2 | TUBB1 2607/4885ALDH1A1 137/4885PTGS1 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.