SCHEMBL16123646

SCHEMBL16123646

CCN(CC)CCCn1c2cc(OC)ccc2c2ccnc(C)c21

nearest known ligand 0.78

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ DYRK1A Q13627 17/20 0.78
▸ HASPIN Q8TF76 4/20 0.75
▸ HTR2A P28223 1/20 0.72
▸ HTR2C P28335 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16102805 0.89 HASPIN (0.94) DYRK1AHASPINHTR2AHTR2C
SCHEMBL30663727 0.89 HASPIN (0.94) DYRK1AHASPINHTR2AHTR2C
SCHEMBL17517503 0.89 DYRK1A (0.88) DYRK1AHASPINHTR2AHTR2C
SCHEMBL13875060 0.89 HASPIN (0.88) DYRK1AHASPINHTR2AHTR2C
SCHEMBL2217125 0.88 DYRK1A (1.00) DYRK1AHASPINHTR2AHTR2C
SCHEMBL17502361 0.87 HASPIN (0.86) DYRK1AHASPINHTR2AHTR2C
SCHEMBL17502363 0.87 HASPIN (0.86) DYRK1AHASPINHTR2AHTR2C
SCHEMBL17517505 0.87 HASPIN (0.86) DYRK1AHASPINHTR2AHTR2C
SCHEMBL3857445 0.87 HASPIN (0.86) DYRK1AHASPINHTR2AHTR2C
SCHEMBL16126058 0.86 DYRK1A (0.57) DYRK1AHASPINHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113416187-A Alkylamine peganine derivatives for promoting bone growth 奥斯特克有限公司 2021-09-21 — — CN claimed
EP-2968284-B1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOQC INC (CA) 2021-04-21 — — EP claimed
EP-3915987-B1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOQC INC (CA) 2023-12-13 — — EP disclosed
EP-3915987-A1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH Osteoqc Inc. (CA) 2021-12-01 — — EP disclosed
CN-113416187-A Alkylamine peganine derivatives for promoting bone growth 奥斯特克有限公司 2021-09-21 — — CN disclosed
CN-105120863-B Alkylamine peganine derivatives for promoting bone growth 奥斯特克有限公司 2021-06-04 — — CN disclosed
EP-2968284-B1 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSTEOQC INC (CA) 2021-04-21 — — EP disclosed
US-20200172538-A1 COMPOUNDS FOR BONE GROWTH OSSIFI THERAPEUTICS LLC 2020-06-04 — — US disclosed
US-20170298059-A1 COMPOUNDS FOR BONE GROWTH OSSIFI THERAPEUTICS LLC 2017-10-19 — — US disclosed
US-20170298059-A1 COMPOUNDS FOR BONE GROWTH OSSIFI THERAPEUTICS LLC 2017-10-19 — — US disclosed
WO-2014153203-A2 ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH OSSIFI INC. (US) 2014-09-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172538-A1 COMPOUNDS FOR BONE GROWTH FGF1, FGF2, BMP2 DYRK1A 4508/4885HASPIN 1246/4885HTR2A 4576/4885
US-20170298059-A1 COMPOUNDS FOR BONE GROWTH FGF1, FGF2, BMP2 DYRK1A 4508/4885HASPIN 1246/4885HTR2A 4576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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