SCHEMBL1612692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12712464	0.92	PGR (0.47)	MMP1MMP9MMP13ADAM17PGR
	SCHEMBL1612196	0.90	HTT (0.41)	RORCSTSREV1MAPTMEN1
	SCHEMBL1613165	0.88	HTT (0.40)	RORCSTSREV1MAPTHTR6
	SCHEMBL1726322	0.87	HTR6 (0.46)	PGRMAPTHTR6MEN1KMT2A
	SCHEMBL1612610	0.87	MAPT (0.39)	RORCSTSMAPTMEN1LMNA
	Hydrochloric Acid SCHEMBL1611755	0.86	HTR6 (0.46)	PGRHTR6MEN1KMT2AERAP1
	SCHEMBL15655489	0.86	HTR6 (0.42)	STSHTR6GPR119RETTGFBR1
	SCHEMBL1726886	0.84	HTR6 (0.51)	PGRHTR6
	Hydrochloric Acid SCHEMBL1611891	0.84	HTR6 (0.51)	PGRHTR6
	SCHEMBL1612319	0.82	HTR6 (0.54)	HTR6MEN1KMT2ATGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.