Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.74 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.74 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.74 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.74 |
| ▸ | LTA4H | P09960 | 1/20 | 0.68 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16128927 | 0.98 | HDAC1 (0.71) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL16127281 | 0.94 | HDAC1 (0.68) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL12960847 | 0.87 | MAPK1 (0.65) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL26709560 | 0.87 | MAPK1 (0.65) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL16128931 | 0.86 | HDAC1 (0.76) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL17404991 | 0.86 | HDAC1 (0.76) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL22793229 | 0.86 | HDAC1 (0.59) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL3523157 | 0.85 | MAPK1 (0.61) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL13577993 | 0.84 | HDAC1 (0.73) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL16128934 | 0.84 | HDAC1 (0.73) | HDAC1HDAC10HDAC6HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407528-B2 | UV-absorbing polymers and formulations thereof | ISP INVESTMENTS LLC (US) | 2019-09-10 | — | — | US | disclosed |
| US-10351523-B2 | UV-absorbing compounds with at least one reactive hydrogen | ISP INVESTMENTS LLC | 2019-07-16 | — | — | US | disclosed |
| US-20180208695-A1 | UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF | ISP INVESTMENTS LLC (US) | 2018-07-26 | — | — | US | disclosed |
| US-20180099927-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS LLC (US) | 2018-04-12 | — | — | US | disclosed |
| US-9920152-B2 | UV-absorbing polymers and formulations thereof | ISP INVESTMENTS LLC (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170114173-A1 | UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF | ISP INVESTMENTS LLC (US) | 2017-04-27 | — | — | US | disclosed |
| US-9540474-B2 | UV-absorbing polymers and formulations thereof | ISP INVESTMENTS LLC (US) | 2017-01-10 | — | — | US | disclosed |
| US-20160002154-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS INC. (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002384-A1 | UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF | ISP INVESTMENTS INC. (US) | 2016-01-07 | — | — | US | disclosed |
| WO-2014149363-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ISP INVESTMENTS INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014149390-A1 | UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF | ISP INVESTMENTS INC. (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10407528-B2 | UV-absorbing polymers and formulations thereof | PUF60, UACA, UMPS | HDAC1 167/4885HDAC10 28/4885HDAC6 116/4885 |
| US-20170114173-A1 | UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF | PUF60, UACA, UMPS | HDAC1 167/4885HDAC10 28/4885HDAC6 116/4885 |
| US-20180208695-A1 | UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF | PUF60, UACA, UMPS | HDAC1 167/4885HDAC10 28/4885HDAC6 116/4885 |
| US-10351523-B2 | UV-absorbing compounds with at least one reactive hydrogen | ERCC1, ERCC4, UNG | HDAC1 1873/4885HDAC10 2542/4885HDAC6 1162/4885 |
| US-20160002154-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ERCC1, ERCC4, UNG | HDAC1 1873/4885HDAC10 2542/4885HDAC6 1162/4885 |
| US-20180099927-A1 | UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN | ERCC1, ERCC4, UNG | HDAC1 1873/4885HDAC10 2542/4885HDAC6 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.