Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16088694 | 0.88 | HTT (0.58) | HPGDALDH1A1KDM4ERCE1KMT2A | |
| SCHEMBL13167369 | 0.83 | LIPG (0.49) | HPGDALDH1A1KMT2AHTTLIPG | |
| SCHEMBL13947262 | 0.79 | HDAC1 (0.56) | HPGDALDH1A1KMT2AHTTGAA | |
| SCHEMBL1286684 | 0.76 | IRAK4 (0.53) | ALDH1A1KDM4EKMT2AHTTGAA | |
| SCHEMBL24323097 | 0.74 | ALDH1A1 (0.45) | HPGDALDH1A1KMT2AHTTLIPG | |
| SCHEMBL1655461 | 0.72 | SMN1; SMN2 (0.56) | HPGDALDH1A1KDM4ETDP1PLA2G1B | |
| SCHEMBL12852529 | 0.72 | MCL1 (0.53) | ALDH1A1GAAPKM | |
| SCHEMBL5213976 | 0.72 | POLB (0.49) | HPGDGAASMN1; SMN2NPC1LIPG | |
| SCHEMBL23611756 | 0.71 | SMN1; SMN2 (0.55) | HPGDALDH1A1KDM4ETDP1HTT | |
| SCHEMBL22994473 | 0.70 | HPGD (0.45) | HPGDKDM4EKMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014151953-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-09-25 | — | — | WO | disclosed |