Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21544262 | 0.86 | PTPN1 (0.34) | PTPN1PTPN6PTPN11 | |
| SCHEMBL30937561 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL16048039 | 0.80 | ALDH1A1 (0.34) | ALDH1A1PTPN1PTPN6PTPN11 | |
| SCHEMBL2032766 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL28091089 | 0.77 | KDM4E (0.42) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL16727104 | 0.72 | KDM4E (0.34) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL5973280 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL11140035 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL29778817 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL29722520 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014151005-A1 | 4-AMINO-6-(HETEROCYCLIC)PICOLINATES AND 6-AMINO-2-2(HETEROCYCLIC) PYRIMIDINE-4-CARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-25 | — | — | WO | disclosed |