Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727104 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1TSHRTDP1TP53 | |
| SCHEMBL6152098 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1TSHRTDP1TP53 | |
| SCHEMBL6589859 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1TSHRTDP1TP53 | |
| SCHEMBL16128805 | 0.77 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1TP53CYP3A4 | |
| SCHEMBL139002 | 0.76 | ALDH1A1 (0.65) | KDM4EALDH1A1TSHRTDP1TP53 | |
| SCHEMBL3704142 | 0.74 | ALDH1A1 (0.34) | KDM4EALDH1A1TSHRTDP1TP53 | |
| SCHEMBL30578150 | 0.73 | ALDH1A1 (0.61) | KDM4EALDH1A1TSHRTDP1TP53 | |
| SCHEMBL28908462 | 0.73 | ALDH1A1 (0.61) | KDM4EALDH1A1TSHRTDP1TP53 | |
| Methane SCHEMBL2038793 | 0.73 | ALDH1A1 (0.61) | KDM4EALDH1A1TSHRTDP1TP53 | |
| SCHEMBL30578152 | 0.73 | ALDH1A1 (0.61) | KDM4EALDH1A1TSHRTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105859725-B | The synthetic method of 5,10 indoline simultaneously [3,2 b] indole derivatives | 天津大学 | 2017-11-17 | — | — | CN | disclosed |
| CN-105859725-A | 5,10-dihydroindolo[3,2-b]indole derivative synthesis method | 天津大学 | 2016-08-17 | — | — | CN | disclosed |