Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.60 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | SMO | Q99835 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097992 | 0.84 | HDAC1 (0.61) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL16098905 | 0.84 | HDAC1 (0.64) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL23229477 | 0.83 | ALDH1A1 (0.86) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL16099086 | 0.83 | HDAC1 (0.60) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL16098149 | 0.83 | TRPV1 (0.62) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL18030845 | 0.83 | NR1H4 (0.67) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL23229663 | 0.83 | KDM4E (0.60) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL18007316 | 0.82 | KDM4E (0.73) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL18007312 | 0.81 | TRPV1 (0.60) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL18030750 | 0.81 | KDM4E (0.65) | KMT2AKDM4ELMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | US | disclosed |
| US-20160052898-A1 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | US | disclosed |
| WO-2014147182-A2 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | AADAC, NAT1, CCNA1 | KMT2A 336/4885KDM4E 995/4885LMNA 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.