Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.86 |
| ▸ | MAPT | P10636 | 5/20 | 0.86 |
| ▸ | LMNA | P02545 | 4/20 | 0.86 |
| ▸ | HPGD | P15428 | 1/20 | 0.86 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | ACLY | P53396 | 6/20 | 0.63 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | FGB | P02675 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922972 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL23229426 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL7144948 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL16129643 | 0.83 | KMT2A (0.65) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL23212328 | 0.83 | STING1 (0.76) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL23226897 | 0.83 | KMT2A (0.82) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL7150693 | 0.81 | HTT (0.69) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL23229473 | 0.81 | ALDH1A1 (0.79) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL7153167 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL7150208 | 0.80 | KMT2A (0.70) | ALDH1A1KMT2AKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112057443-B | Medical application of benzene sulfonamide compound and pharmaceutical composition thereof | 中国药科大学 | 2022-10-14 | — | — | CN | disclosed |
| WO-2021068951-A1 | MEDICAL USE OF BENZENESULFONAMIDE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |
| CN-112057443-A | Medical application of benzene sulfonamide compound and pharmaceutical composition thereof | 中国药科大学 | 2020-12-11 | — | — | CN | disclosed |