Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18794796 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL16129653 | 0.71 | RAB9A (0.49) | ALDH1A1GAAHPGDSMN1; SMN2MAPT | |
| SCHEMBL10412163 | 0.69 | ALDH1A1 (0.48) | ALDH1A1GAAALOX12HTTHPGD | |
| SCHEMBL14404552 | 0.69 | — | — | |
| SCHEMBL3036286 | 0.69 | — | — | |
| SCHEMBL3036288 | 0.69 | — | — | |
| SCHEMBL28732796 | 0.68 | ALDH1A1 (0.46) | ALDH1A1GAAALOX12HTTHPGD | |
| SCHEMBL13229698 | 0.67 | ALDH1A1 (0.41) | ALDH1A1GAAALOX12HTTHPGD | |
| SCHEMBL25690630 | 0.67 | RECQL (0.41) | ALDH1A1GAAALOX12HTTHPGD | |
| SCHEMBL4160974 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152115-A1 | N-,C-DISUBSTITUTED AZOLES FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2014-09-25 | — | — | WO | disclosed |