Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 6/20 | 0.50 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098936 | 0.83 | WNT3A (0.73) | SMN1; SMN2WNT3AMEN1KMT2A | |
| SCHEMBL16102995 | 0.82 | WNT3A (0.73) | NPC1RAB9AWNT3AMEN1KMT2A | |
| SCHEMBL17539213 | 0.82 | ALDH1A1 (0.51) | HTTNPC1MITFALDH1A1RAB9A | |
| SCHEMBL16129614 | 0.82 | MEN1 (0.54) | HTTSMN1; SMN2SETD7PRMT1MEN1 | |
| SCHEMBL16098059 | 0.82 | WNT3A (0.73) | ALDH1A1SMN1; SMN2WNT3AMEN1MAPT | |
| SCHEMBL16129646 | 0.81 | SMN1; SMN2 (0.49) | HTTNPC1MITFALDH1A1RAB9A | |
| SCHEMBL16104957 | 0.80 | WNT3A (0.55) | WNT3AMEN1KMT2A | |
| SCHEMBL16105048 | 0.80 | SMN1; SMN2 (0.59) | HTTNPC1MITFALDH1A1RAB9A | |
| SCHEMBL16129676 | 0.79 | HDAC8 (0.64) | HTTNPC1MITFALDH1A1RAB9A | |
| SCHEMBL16098779 | 0.79 | SMN1; SMN2 (0.47) | HTTNPC1MITFALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | US | disclosed |
| WO-2014147182-A2 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | AADAC, NAT1, CCNA1 | HTT 1838/4885NPC1 933/4885MITF 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.