Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098533 | 0.93 | ALDH1A1 (0.86) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL6813402 | 0.93 | ALDH1A1 (0.77) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL16129644 | 0.85 | TDP1 (0.54) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL19034437 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL4189026 | 0.83 | POLB (0.78) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL16099179 | 0.82 | ALDH1A1 (0.71) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL16099264 | 0.81 | LMNA (0.66) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL6809707 | 0.81 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL6813418 | 0.81 | MEN1 (0.73) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL14383794 | 0.81 | ALDH1A1 (0.73) | ALDH1A1CYP3A4TSHRTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | US | disclosed |
| US-20160052898-A1 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | US | disclosed |
| US-20160052898-A1 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | US | disclosed |
| WO-2014147182-A2 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | AADAC, NAT1, CCNA1 | ALDH1A1 325/4885CYP3A4 1384/4885TSHR 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.