Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | WNT3A | P56704 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098478 | 0.93 | ALDH1A1 (0.57) | ALDH1A1KDM4EWNT3ASMN1; SMN2LMNA | |
| SCHEMBL16098430 | 0.93 | WNT3A (0.59) | ALDH1A1WNT3ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16129627 | 0.90 | WNT3A (0.59) | ALDH1A1WNT3ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16097297 | 0.90 | WNT3A (0.73) | ALDH1A1WNT3ASMN1; SMN2MAPTALOX15 | |
| SCHEMBL16097288 | 0.89 | WNT3A (0.57) | ALDH1A1KDM4EWNT3ASMN1; SMN2LMNA | |
| SCHEMBL16129727 | 0.89 | WNT3A (0.60) | ALDH1A1WNT3ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16097700 | 0.88 | HDAC1 (0.63) | ALDH1A1WNT3ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16129688 | 0.88 | WNT3A (0.55) | ALDH1A1WNT3ASMN1; SMN2LMNAMAPT | |
| SCHEMBL16129698 | 0.88 | WNT3A (0.59) | WNT3ASMN1; SMN2MAPTALOX15 | |
| SCHEMBL16099313 | 0.87 | WNT3A (0.59) | ALDH1A1WNT3ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | US | disclosed |
| WO-2014147182-A2 | NOVEL COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160052898-A1 | NOVEL COMPOUNDS | AADAC, NAT1, CCNA1 | ALDH1A1 325/4885KDM4E 995/4885WNT3A 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.