Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATXN2 | Q99700 | 7/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129761 | 0.95 | F2RL1 (0.43) | ATXN2ENPP2F2RL1TACR1GPR119 | |
| SCHEMBL16129759 | 0.90 | TACR1 (0.41) | ATXN2ENPP2F2RL1TACR1GPR119 | |
| SCHEMBL16129775 | 0.90 | ENPP2 (0.45) | ATXN2ENPP2TACR1GPR119MAPT | |
| SCHEMBL16099936 | 0.87 | ENPP2 (0.44) | ATXN2ENPP2TACR1FAAH | |
| SCHEMBL16129890 | 0.85 | ENPP2 (0.44) | ATXN2ENPP2TACR1FAAH | |
| SCHEMBL16129897 | 0.84 | TACR1 (0.47) | ATXN2ENPP2TACR1GPR119MAPT | |
| SCHEMBL16129754 | 0.84 | ENPP2 (0.39) | ATXN2ENPP2TACR1GPR119STS | |
| SCHEMBL16100530 | 0.82 | ENPP2 (0.46) | ATXN2ENPP2TACR1FAAH | |
| SCHEMBL16100799 | 0.82 | ENPP2 (0.43) | ATXN2ENPP2TACR1FAAH | |
| SCHEMBL16129736 | 0.81 | ENPP2 (0.43) | ATXN2ENPP2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152725-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-09-25 | — | — | WO | disclosed |