Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 17/20 | 0.43 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129834 | 0.94 | ENPP2 (0.39) | ENPP2ATXN2HTR2AABATSIGMAR1 | |
| SCHEMBL16129763 | 0.89 | ENPP2 (0.43) | ENPP2ATXN2FAAHHTR2AABAT | |
| SCHEMBL16129894 | 0.89 | ENPP2 (0.43) | ENPP2ATXN2FAAHHTR2AABAT | |
| SCHEMBL16129744 | 0.88 | ENPP2 (0.43) | ENPP2ATXN2KCNH2 | |
| SCHEMBL16129902 | 0.87 | ENPP2 (0.46) | ENPP2ATXN2KCNH2SCN9A | |
| SCHEMBL16100530 | 0.87 | ENPP2 (0.46) | ENPP2ATXN2FAAHKCNH2 | |
| SCHEMBL16129775 | 0.86 | ENPP2 (0.45) | ENPP2ATXN2KCNH2 | |
| SCHEMBL16129850 | 0.86 | SCN9A (0.38) | ENPP2ATXN2HTR2AABATSIGMAR1 | |
| SCHEMBL16129768 | 0.86 | ENPP2 (0.39) | ENPP2ATXN2HTR2AABATSIGMAR1 | |
| SCHEMBL16129754 | 0.85 | ENPP2 (0.39) | ENPP2ATXN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152725-A1 | S1P AND/OR ATX MODULATING AGENTS | BIOGEN IDEC MA INC. (US) | 2014-09-25 | — | — | WO | disclosed |