Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.50 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402110 | 0.81 | AR (0.51) | ARPGR | |
| SCHEMBL4404032 | 0.81 | AR (0.51) | ARPGR | |
| SCHEMBL18856260 | 0.81 | AR (0.51) | ARPGR | |
| SCHEMBL1190703 | 0.78 | AR (0.49) | ARPGR | |
| SCHEMBL189787 | 0.78 | AR (0.49) | ARPGR | |
| SCHEMBL21936494 | 0.77 | AR (0.47) | ARPGR | |
| SCHEMBL22834021 | 0.77 | AR (0.47) | ARPGR | |
| SCHEMBL18084255 | 0.77 | FFAR4 (0.40) | AR | |
| SCHEMBL12960442 | 0.74 | AR (0.45) | ARPGR | |
| SCHEMBL110567 | 0.74 | AR (0.56) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9844528-B2 | SARMs and method of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2017-12-19 | — | — | US | disclosed |
| EP-2871177-A1 | Solid form of (R) or (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide | GTX, Inc. (US) | 2015-05-13 | — | — | EP | disclosed |
| US-8846756-B2 | Substituted acylanilides and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-09-30 | — | — | US | disclosed |