Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 19/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21936494 | 0.81 | AR (0.47) | ARPGR | |
| SCHEMBL4404032 | 0.79 | AR (0.51) | ARPGR | |
| SCHEMBL21936738 | 0.78 | AR (0.49) | ARPGR | |
| SCHEMBL16471305 | 0.76 | TRPV4 (0.44) | AR | |
| SCHEMBL189787 | 0.76 | AR (0.49) | ARPGR | |
| SCHEMBL16471313 | 0.76 | EPAS1 (0.33) | — | |
| SCHEMBL16471349 | 0.76 | — | — | |
| SCHEMBL4402110 | 0.76 | AR (0.51) | ARPGR | |
| SCHEMBL18856260 | 0.76 | AR (0.51) | ARPGR | |
| SCHEMBL16130164 | 0.74 | AR (0.50) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148416-A1 | INDUSTRIAL PROCESS FOR THE PREPARATION OF ENZALUTAMIDE | OLON S.P.A. (IT) | 2018-05-31 | — | — | US | disclosed |
| US-20160016925-A1 | Substituted (R)-3-(4-methylcarbamoyl-3-fluorophenylamino)tetrahydrofuran-3-encarboxylic acid (variants) and ester thereof, method for preparation and use | Ivachtchenko, Alexandre Vasilievich (US) | 2016-01-21 | — | — | US | disclosed |
| US-20120251551-A1 | Substituted (Heteroarylmethyl)thiohydantoins | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120251551-A1 | Substituted (Heteroarylmethyl)thiohydantoins | TPMT, BPHL, VHL | AR 58/4885PGR 1590/4885 |
| US-20160016925-A1 | Substituted (R)-3-(4-methylcarbamoyl-3-fluorophenylamino)tetrahydrofuran-3-encarboxylic acid (variants) and ester thereof, method for preparation and use | AR, SRD5A1, CYP19A1 | AR 1/4885PGR 263/4885 |
| US-20180148416-A1 | INDUSTRIAL PROCESS FOR THE PREPARATION OF ENZALUTAMIDE | AR, HDAC11, HDAC1 | AR 1/4885PGR 2472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.