Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608175 | 0.82 | TDP1 (0.44) | TDP1TSHRHPGDMEN1POLB | |
| SCHEMBL1110727 | 0.81 | — | — | |
| SCHEMBL28496420 | 0.81 | — | — | |
| SCHEMBL905193 | 0.81 | — | — | |
| SCHEMBL2608194 | 0.81 | TDP1 (0.42) | TDP1TSHRHPGDMEN1POLB | |
| SCHEMBL16130358 | 0.80 | ALDH1A1 (0.39) | TDP1TSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL16130378 | 0.79 | ALDH1A1 (0.42) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| SCHEMBL7760169 | 0.78 | ALDH1A1 (0.48) | TDP1TSHRHPGDMEN1POLB | |
| SCHEMBL2132279 | 0.77 | TDP1 (0.36) | TDP1TSHRHPGDMEN1POLB | |
| SCHEMBL11285627 | 0.77 | TDP1 (0.36) | TDP1TSHRHPGDMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846638-B2 | Macrocyclic nucleoside phosphoramidate derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-8846638-B2 | Macrocyclic nucleoside phosphoramidate derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2014-09-30 | — | — | US | disclosed |