Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001339 | 1.00 | LMNA (0.49) | LMNAKMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL10591560 | 1.00 | LMNA (0.49) | LMNAKMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL8589167 | 0.88 | LMNA (0.53) | LMNAKMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL8589165 | 0.88 | LMNA (0.53) | LMNAKMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL10001340 | 0.85 | LMNA (0.45) | LMNAKMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL25304810 | 0.84 | LMNA (0.50) | LMNAKMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL7641597 | 0.84 | LMNA (0.50) | LMNAKMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL30929669 | 0.84 | ALDH1A1 (0.48) | LMNAMAPTHPGDRAB9ATP53 | |
| SCHEMBL7641591 | 0.84 | LMNA (0.50) | LMNAKMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL199971 | 0.82 | ALDH1A1 (0.58) | LMNAKMT2AMAPTHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846876-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | Abrx, Inc. (US) | 2014-09-30 | — | — | US | disclosed |