SCHEMBL16133170

SCHEMBL16133170

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2ccc3c(c2)c2cccc4c5ccccc5c5cccc3c5c42)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSPO P30536 2/20 0.36
NR4A2 P43354 2/20 0.35
NR3C1 P04150 1/20 0.34
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
HDAC4 P56524 1/20 0.33
RAC2 P15153 1/20 0.32
RAC3 P60763 1/20 0.32
CDC42 P60953 1/20 0.32
RAC1 P63000 1/20 0.32
PIM1 P11309 1/20 0.32
FAAH O00519 2/20 0.32
MGLL Q99685 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21034917 0.98 KDM4E (0.39) ATMKDM4EL3MBTL1TSPONR4A2
SCHEMBL21034919 0.95 L3MBTL1 (0.44) ATMKDM4EL3MBTL1TSPONR4A2
SCHEMBL21034918 0.95 L3MBTL1 (0.44) ATMKDM4EL3MBTL1TSPONR4A2
SCHEMBL20996066 0.95 KDM4E (0.39) ATMKDM4EL3MBTL1TSPONR4A2
SCHEMBL21035228 0.94 L3MBTL1 (0.44) ATMKDM4EL3MBTL1TSPONR4A2
SCHEMBL18675906 0.94 KDM4E (0.42) ATMKDM4EL3MBTL1TSPONR4A2
SCHEMBL16373519 0.94 KDM4E (0.42) ATMKDM4EL3MBTL1TSPONR4A2
SCHEMBL20232138 0.94 KDM4E (0.42) ATMKDM4EL3MBTL1TSPONR4A2
SCHEMBL21035296 0.92 L3MBTL1 (0.47) ATMKDM4EL3MBTL1TSPONR4A2
SCHEMBL15479810 0.92 ATM (0.45) ATMKDM4EL3MBTL1TSPOEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed