SCHEMBL21035296

SCHEMBL21035296

c1ccc(-c2ccc3c(c2)c2ccccc2c2c4ccc(-n5c6ccccc6c6ccccc65)cc4c4ccccc4c32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ATM Q13315 1/20 0.47
HDAC4 P56524 1/20 0.39
TSPO P30536 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
KMT2A Q03164 2/20 0.34
IL1R1 P14778 1/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
NR4A2 P43354 1/20 0.33
RAC2 P15153 1/20 0.33
RAC3 P60763 1/20 0.33
CDC42 P60953 1/20 0.33
RAC1 P63000 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21034919 0.97 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL21034918 0.97 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL21036083 0.95 L3MBTL1 (0.53) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL27309866 0.95 L3MBTL1 (0.52) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL21034917 0.94 KDM4E (0.39) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL15479845 0.93 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL21035229 0.92 L3MBTL1 (0.50) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL16133170 0.92 ATM (0.38) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL23156756 0.92 L3MBTL1 (0.48) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL20232127 0.92 L3MBTL1 (0.48) L3MBTL1KDM4EATMHDAC4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT JNC CORPORATION (JP) 2019-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190165279-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, LGR4, OR51E2 L3MBTL1 834/4885KDM4E 396/4885ATM 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.