SCHEMBL16133237

SCHEMBL16133237

c1ccc(-c2cccc3c2sc2c(-c4cccc(-c5ccc6c(c5)c5ccccc5c5cc7c8ccccc8c8ccccc8c7cc65)c4)cccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.47
LIMK1 P53667 2/20 0.44
F9 P00740 1/20 0.37
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
PRKDC P78527 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
MAP3K8 P41279 4/20 0.34
PIM1 P11309 1/20 0.34
PIM3 Q86V86 1/20 0.34
TDO2 P48775 1/20 0.34
MAPK1 P28482 1/20 0.33
MAP2K1 Q02750 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
S1PR4 O95977 1/20 0.33
S1PR5 Q9H228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1687987 0.98 ALOX5 (0.48) ALOX5LIMK1F9HSD17B1HSD17B2
SCHEMBL17425730 0.97 ALOX5 (0.47) ALOX5LIMK1F9HSD17B1HSD17B2
SCHEMBL17057262 0.97 ALOX5 (0.47) ALOX5LIMK1F9HSD17B1HSD17B2
SCHEMBL17775867 0.97 ALOX5 (0.49) ALOX5LIMK1F9HSD17B1HSD17B2
SCHEMBL16133243 0.97 ALOX5 (0.49) ALOX5LIMK1F9HSD17B1HSD17B2
SCHEMBL17052846 0.95 ALOX5 (0.48) ALOX5LIMK1F9PRKDCCYP1A1
SCHEMBL17057271 0.95 ALOX5 (0.48) ALOX5LIMK1F9PRKDCCYP1A1
SCHEMBL17052848 0.95 ALOX5 (0.48) ALOX5LIMK1F9PRKDCCYP1A1
SCHEMBL18876538 0.95 ALOX5 (0.48) ALOX5LIMK1F9PRKDCCYP1A1
SCHEMBL22789795 0.95 ALOX5 (0.50) ALOX5LIMK1F9HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed