SCHEMBL17057271

SCHEMBL17057271

c1ccc(-c2ccc(-c3cccc(-c4cccc5c4sc4c(-c6cccc(-c7cccc(-c8ccc9c%10ccccc%10c%10ccccc%10c9c8)c7)c6)cccc45)c3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.48
LIMK1 P53667 3/20 0.42
MAP3K8 P41279 4/20 0.37
PIM3 Q86V86 2/20 0.37
PIM1 P11309 1/20 0.37
PRKDC P78527 2/20 0.36
MAPK1 P28482 1/20 0.36
MAP2K1 Q02750 1/20 0.36
S1PR4 O95977 1/20 0.36
S1PR5 Q9H228 1/20 0.36
PTGER1 P34995 1/20 0.36
PTGER4 P35408 1/20 0.36
PTGER3 P43115 1/20 0.36
PTGER2 P43116 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
APAF1 O14727 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17052848 1.00 ALOX5 (0.48) ALOX5LIMK1MAP3K8PIM3PIM1
SCHEMBL18876538 1.00 ALOX5 (0.48) ALOX5LIMK1MAP3K8PIM3PIM1
SCHEMBL17052846 1.00 ALOX5 (0.48) ALOX5LIMK1MAP3K8PIM3PIM1
SCHEMBL17425730 0.98 ALOX5 (0.47) ALOX5LIMK1MAP3K8PIM3PIM1
SCHEMBL17057262 0.98 ALOX5 (0.47) ALOX5LIMK1MAP3K8PIM3PIM1
SCHEMBL10018878 0.98 ALOX5 (0.49) ALOX5LIMK1MAP3K8PIM3PIM1
SCHEMBL1687987 0.97 ALOX5 (0.48) ALOX5LIMK1MAP3K8PIM3PIM1
SCHEMBL22789795 0.97 ALOX5 (0.50) ALOX5LIMK1MAP3K8PIM3PIM1
SCHEMBL16133237 0.95 ALOX5 (0.47) ALOX5LIMK1MAP3K8PIM3PIM1
SCHEMBL17775867 0.95 ALOX5 (0.49) ALOX5LIMK1MAP3K8PIM3PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9190620-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-11-17 US disclosed
US-20150249221-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150249221-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES DDT, TERF2, DBF4 ALOX5 791/4885LIMK1 456/4885MAP3K8 3439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.