SCHEMBL16133282

SCHEMBL16133282

c1cc(-c2ccc3c(c2)c2cccc4c5ccccc5c5cccc3c5c42)cc(-c2cccc3c2oc2ccc(-n4c5ccccc5c5ccccc54)cc23)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PRKDC P78527 10/20 0.37
GGPS1 O95749 1/20 0.35
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
PLA2G10 O15496 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PIM1 P11309 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
PIM3 Q86V86 1/20 0.30
PIM2 Q9P1W9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16133284 0.97 ALOX5 (0.44) ALOX5PRKDCGGPS1PRMT5WDR77
SCHEMBL14733733 0.97 ALOX5 (0.44) ALOX5PRKDCGGPS1PLA2G2APLA2G4A
SCHEMBL16133310 0.96 ALOX5 (0.43) ALOX5PRKDCGGPS1PLA2G2APLA2G4A
SCHEMBL21425719 0.93 ALOX5 (0.47) ALOX5PRKDCGGPS1PRMT5WDR77
SCHEMBL16133307 0.92 ALOX5 (0.46) ALOX5PRKDCGGPS1PRMT5WDR77
SCHEMBL16133295 0.90 ALOX5 (0.48) ALOX5PRKDCGGPS1PRMT5WDR77
SCHEMBL15294176 0.90 ALOX5 (0.48) ALOX5PRKDCGGPS1PLA2G2APLA2G4A
SCHEMBL781143 0.90 ALOX5 (0.48) ALOX5PRKDCGGPS1PRMT5WDR77
SCHEMBL16573892 0.90 ALOX5 (0.50) ALOX5PRKDCGGPS1PLA2G2APLA2G4A
SCHEMBL16133280 0.90 ALOX5 (0.40) ALOX5PRKDCGGPS1PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed