SCHEMBL16133307

SCHEMBL16133307

c1cc(-c2ccc3c(c2)c2ccccc2c2cc4c5ccccc5c5ccccc5c4cc32)c2oc3ccc(-n4c5ccccc5c5ccccc54)cc3c2c1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.46
PRKDC P78527 5/20 0.40
GGPS1 O95749 1/20 0.35
ATM Q13315 2/20 0.34
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
PTPRF P10586 3/20 0.32
PTPN2 P17706 3/20 0.32
PTPN1 P18031 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21425719 0.99 ALOX5 (0.47) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL16133310 0.96 ALOX5 (0.43) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL14733733 0.95 ALOX5 (0.44) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL16133284 0.95 ALOX5 (0.44) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL23433448 0.93 ALOX5 (0.52) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL16133282 0.92 ALOX5 (0.42) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL20698225 0.92 ALOX5 (0.49) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL1687791 0.92 ALOX5 (0.51) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL1687724 0.92 ALOX5 (0.51) ALOX5PRKDCGGPS1ATMKDM4E
SCHEMBL459813 0.92 ALOX5 (0.51) ALOX5PRKDCGGPS1ATMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed