Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16134346 | 1.00 | LMNA (0.36) | LMNACYP2C9 | |
| SCHEMBL16134347 | 0.89 | PIK3CD (0.31) | LMNACYP2C9 | |
| SCHEMBL16867072 | 0.86 | LMNA (0.34) | LMNACYP2C9 | |
| SCHEMBL10171772 | 0.76 | LMNA (0.39) | LMNACYP2C9 | |
| SCHEMBL18725576 | 0.75 | LMNA (0.31) | LMNACYP2C9 | |
| SCHEMBL13708301 | 0.74 | LMNA (0.36) | LMNACYP2C9 | |
| SCHEMBL16134344 | 0.74 | CYP2C19 (0.46) | — | |
| SCHEMBL25788681 | 0.73 | PPARG (0.32) | LMNACYP2C9 | |
| SCHEMBL27192588 | 0.72 | LMNA (0.36) | LMNACYP2C9 | |
| SCHEMBL21615771 | 0.71 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187498-B2 | Compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | MICROBIAL CHEM RES FOUND (JP) | 2015-07-02 | — | — | US | disclosed |
| US-8981123-B2 | Compound and asymmetric synthesis reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140296539-A1 | Compound and Asymmetric Synthesis Reaction | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183807-A1 | Compound and Asymmetric Synthesis Reaction | CYP2E1, REV1, CYP19A1 | LMNA 3936/4885CYP2C9 62/4885 |
| US-20140296539-A1 | Compound and Asymmetric Synthesis Reaction | CYP2E1, REV1, CYP19A1 | LMNA 3936/4885CYP2C9 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.