Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MAX | P61244 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16137801 | 0.81 | MEN1 (0.51) | KMT2AMEN1IDO1L3MBTL1TDP1 | |
| SCHEMBL14933670 | 0.73 | IDO1 (0.69) | KMT2AMEN1IDO1L3MBTL1MYC | |
| SCHEMBL5303826 | 0.71 | ATM (0.57) | KMT2AMEN1MAPK1L3MBTL1MAPT | |
| SCHEMBL19269465 | 0.71 | MAPT (0.42) | KMT2AMEN1TNFMAPK1L3MBTL1 | |
| SCHEMBL14933689 | 0.68 | TNF (0.83) | KMT2AMEN1TNFMAPK1L3MBTL1 | |
| SCHEMBL10240415 | 0.68 | TNF (0.39) | KMT2AMEN1TNFMAPK1L3MBTL1 | |
| SCHEMBL3500163 | 0.68 | GLO1 (0.41) | KMT2AMEN1MAPK1MAPTNPC1 | |
| SCHEMBL20440865 | 0.68 | MAPT (0.44) | KMT2AMEN1MAPK1L3MBTL1MAPT | |
| SCHEMBL10412855 | 0.66 | HPGD (0.52) | KMT2AMEN1MAPK1TDP1RAPGEF4 | |
| SCHEMBL11190236 | 0.66 | ADRA2A (0.52) | KMT2AMEN1MAPK1MAPTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096554-B2 | Drugs for inhibiting p38 and uses thereof | Universidad Autónoma de Madrid (ES) | 2015-08-04 | — | — | US | disclosed |
| US-20140296308-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | Universidad Autónoma de Madrid (ES) | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296308-A1 | DRUGS FOR INHIBITING P38 AND USES THEREOF | MAPK1, MAPK4, MAPK8 | KMT2A 3069/4885MEN1 3940/4885IDO1 1545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.