SCHEMBL1613588

SCHEMBL1613588

NC(Cc1ccc(F)cc1)P(=O)(O)O

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 8/20 0.67
LAP3 P28838 5/20 0.67
ERAP2 Q6P179 4/20 0.44
ERAP1 Q9NZ08 2/20 0.44
TRPA1 O75762 1/20 0.43
CA12 O43570 1/20 0.43
MMP2 P08253 1/20 0.43
PTPRC P08575 1/20 0.41
PTPN1 P18031 1/20 0.41
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15720090 0.82 ANPEP (0.69) ANPEPLAP3ERAP2ERAP1
SCHEMBL10621653 0.82 ANPEP (0.69) ANPEPLAP3ERAP2ERAP1
SCHEMBL9472683 0.81 ANPEP (0.67) ANPEPLAP3ERAP2ERAP1CA12
SCHEMBL8740148 0.80 LAP3 (1.00) ANPEPLAP3ERAP2ERAP1
SCHEMBL2375608 0.80 LAP3 (1.00) ANPEPLAP3ERAP2ERAP1
Bromide SCHEMBL15397852 0.78 LAP3 (0.96) ANPEPLAP3ERAP2ERAP1
SCHEMBL9472647 0.77 ANPEP (0.66) ANPEPLAP3ERAP2MMP2THRA
SCHEMBL6802049 0.77 ANPEP (0.61) ANPEPLAP3ERAP2ERAP1
SCHEMBL7392119 0.77 ANPEP (0.61) ANPEPLAP3ERAP2ERAP1MMP2
SCHEMBL27997874 0.74 LAP3 (0.58) ANPEPLAP3TRPA1THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5189030-A Controlling phytopathogens CIBA-GEIGY CORPORATION (US) 1993-02-23 US claimed
EP-0207890-B1 MICROBICIDAL COMPOSITION CIBA-GEIGY AG (CH) 1990-03-14 EP claimed
EP-0207890-A1 Microbicidal composition CIBA-GEIGY AG (CH) 1987-01-07 EP claimed
CN-104277072-B A kind of preparation method of (E)-2-aryl vinyl phosphate derivatives JIANGSU CHINASUN SPECIALTY PRODUCTS CO.,LTD. (CN) 2016-04-13 CN disclosed
CN-104277072-A Method for preparing (E)-2-aryl vinyl phosphonate derivatives CHINASUN SPECIALTY PRODUCTS CO LTD 2015-01-14 CN disclosed
US-20130017582-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON HOLDINGS, LLC (US) 2013-01-17 US disclosed
US-8338143-B2 Enhanced production of paclitaxel and taxanes by cell cultures of Taxus species PHYTON HOLDINGS, LLC (US) 2012-12-25 US disclosed
US-20110086397-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON HOLDINGS, LLC (US) 2011-04-14 US disclosed
US-20080108115-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES DFB BIOTECH, INCORPORATED (US) 2008-05-08 US disclosed
US-7264951-B1 Enhanced production of taxol and taxanes by cell cultures of Taxus species PHYTON, INC. (US) 2007-09-04 US disclosed
EP-0954596-B1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON INC (US) 2006-01-04 EP disclosed
EP-1538214-A1 Enhanced production of taxanes by cell cultures of taxus species PHYTON, INC. (US) 2005-06-08 EP disclosed
EP-1398384-A1 Enhanced production of taxanes by cell cultures of taxus species Phyton Inc. (US) 2004-03-17 EP disclosed
EP-0954596-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES PHYTON, INC. (US) 1999-11-10 EP disclosed
WO-1997044476-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON, INC. (US) 1997-11-27 WO disclosed
US-5189030-A Controlling phytopathogens CIBA-GEIGY CORPORATION (US) 1993-02-23 US disclosed
EP-0207890-B1 MICROBICIDAL COMPOSITION CIBA-GEIGY AG (CH) 1990-03-14 EP disclosed
EP-0207890-A1 Microbicidal composition CIBA-GEIGY AG (CH) 1987-01-07 EP disclosed