SCHEMBL2375608

SCHEMBL2375608

NC(Cc1ccccc1)P(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 8/20 1.00
ANPEP P15144 8/20 1.00
ERAP2 Q6P179 5/20 0.67
ERAP1 Q9NZ08 4/20 0.67
ACP3 P15309 1/20 0.58
ALPI P09923 1/20 0.53
PKM P14618 1/20 0.53
PTGS1 P23219 1/20 0.53
XIAP P98170 1/20 0.53
SLC7A5 Q01650 1/20 0.53
EPHX1 P07099 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8740148 1.00 LAP3 (1.00) LAP3ANPEPERAP2ERAP1ACP3
Bromide SCHEMBL15397852 0.98 LAP3 (0.96) LAP3ANPEPERAP2ERAP1ACP3
SCHEMBL7529859 0.88 LAP3 (0.78) LAP3ANPEPERAP2ERAP1ACP3
SCHEMBL7526774 0.88 LAP3 (0.78) LAP3ANPEPERAP2ERAP1ACP3
Hydrochloric Acid SCHEMBL8689730 0.86 LAP3 (0.75) LAP3ANPEPERAP2ERAP1ACP3
Hydrochloric Acid SCHEMBL8693019 0.86 LAP3 (0.75) LAP3ANPEPERAP2ERAP1ACP3
Bromide SCHEMBL9004890 0.86 LAP3 (0.75) LAP3ANPEPERAP2ERAP1ACP3
SCHEMBL10622084 0.84 LAP3 (0.71) LAP3ANPEPERAP1PTGS1
SCHEMBL10621653 0.82 ANPEP (0.69) LAP3ANPEPERAP2ERAP1SLC7A5
SCHEMBL15720090 0.82 ANPEP (0.69) LAP3ANPEPERAP2ERAP1SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0207890-B1 MICROBICIDAL COMPOSITION CIBA-GEIGY AG (CH) 1990-03-14 EP claimed
EP-0207890-A1 Microbicidal composition CIBA-GEIGY AG (CH) 1987-01-07 EP claimed
EP-3653215-A1 THERANOSTIC INHIBITORS AND ACTIVITY-BASED PROBES FOR THE KLK7 PROTEASE University of Patras (GR) 2020-05-20 EP disclosed
CN-105073757-B Dyeing process using a hair-dyeing precursor obtained from an iridoid, composition, precursor and device comprising such a precursor 莱雅公司 2019-12-17 CN disclosed
CN-106674274-B A kind of phosphate mineral inhibitor and preparation method thereof and purposes 中蓝连海设计研究院有限公司 2019-04-26 CN disclosed
EP-2978767-B1 DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME OREAL (FR) 2018-10-03 EP disclosed
CN-106674274-A Phosphate mineral inhibitor as well as preparation method and use thereof 中蓝连海设计研究院 2017-05-17 CN disclosed
CN-105899526-A Cytotoxic peptides and conjugates thereof 诺华股份有限公司 2016-08-24 CN disclosed
EP-2978749-A1 OPTIONALLY PROTECTED IRIDOID-DERIVED COMPOUNDS, COMPOSITION INCLUDING SAME, USE AS A DYE FOR KERATIN FIBRES AND DEVICES L'Oréal (FR) 2016-02-03 EP disclosed
EP-2978767-A1 DYEING METHOD USING A HAIR-DYEING PRECURSOR OBTAINED FROM IRIDOIDS, COMPOSITION, PRECURSOR AND DEVICE INCLUDING SAME L'OREAL (FR) 2016-02-03 EP disclosed
CN-105101947-A Dyeing method using iridoid compound and apparatus therefor OREAL 2015-11-25 CN disclosed
US-20050221456-A1 Use of indanoyl amide to stimulate secondary metabolism in Taxus sp. PHYTON BIOTECH, INC. (US) 2005-10-06 US disclosed
US-5703263-A USEFUL AS ANTIBIOTICS AND/OR AS INTERMEDIATES IN THE PREPARATION OF PHOSPHORUS-CONTAINING ANALOGS OF PEPTIDES MONSANTO COMPANY (US) 1997-12-30 US disclosed
US-5654462-A CATALYTIC HYDROGENATION OF OLEFINS; ANTIBIOTICS; ENZYME INHIBITOR MONSANTO COMPANY (US) 1997-08-05 US disclosed
US-5189030-A Controlling phytopathogens CIBA-GEIGY CORPORATION (US) 1993-02-23 US disclosed
EP-0207890-B1 MICROBICIDAL COMPOSITION CIBA-GEIGY AG (CH) 1990-03-14 EP disclosed
US-4849414-A HYPOTENSIVE E. R. SQUIBB & SONS, INC. (US) 1989-07-18 US disclosed
EP-0249445-A2 Substituted aminoalkanoylaminoalkyl phosphonate angiotensin converting enzyme inhibitors E.R. Squibb & Sons, Inc. (US) 1987-12-16 EP disclosed
US-4379146-A Substituted phosphonamides as antihypertensives MERCK & CO., INC. (US) 1983-04-05 US disclosed
EP-0058427-A2 Substituted phosphonamides, a process for preparing the same and a pharmaceutical composition which is useful in the treatment of hypertension MERCK & CO. INC. (US) 1982-08-25 EP disclosed