SCHEMBL16137705

SCHEMBL16137705

C=C(C)C(=O)Oc1ccc2cc(C3(c4ccc5cc(OC(=O)C(=C)C)ccc5c4)c4ccccc4-c4cc5ccccc5cc43)ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
PDK2 Q15119 5/20 0.36
KMT2A Q03164 8/20 0.35
MEN1 O00255 6/20 0.35
MAPT P10636 4/20 0.35
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KDM4E B2RXH2 2/20 0.35
OPRK1 P41145 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 1/20 0.33
ATM Q13315 1/20 0.33
USP2 O75604 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.32
GLA P06280 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16137706 0.95 ELANE (0.44) ELANEKMT2AMEN1MAPTSMN1; SMN2
SCHEMBL16137609 0.94 ELANE (0.45) ELANEESR1ESR2PDK2KMT2A
SCHEMBL22639282 0.93 PDGFRB (0.39) ELANEESR1ESR2PDK2KMT2A
SCHEMBL23442222 0.92 ELANE (0.46) ELANEESR1ESR2PDK2KMT2A
SCHEMBL21976004 0.89 KMT2A (0.42) ELANEESR1ESR2PDK2KMT2A
SCHEMBL25002487 0.88 ELANE (0.38) ELANEPDK2KMT2AMEN1MAPT
SCHEMBL23992481 0.87 ELANE (0.50) ELANEPDK2KMT2AMEN1MAPT
SCHEMBL21976001 0.87 ELANE (0.39) ELANEESR1ESR2PDK2KMT2A
SCHEMBL19399684 0.87 ELANE (0.39) ELANEESR1ESR2PDK2KMT2A
SCHEMBL23992518 0.86 ELANE (0.31) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230056225-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT TOKYO OHKA KOGYO CO., LTD. (JP) 2023-02-23 US disclosed
US-20230038195-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT TOKYO OHKA KOGYO CO., LTD. (JP) 2023-02-09 US disclosed
US-20200139433-A1 METHOD FOR PRODUCING SURFACE-MODIFIED METAL OXIDE FINE PARTICLE, METHOD FOR PRODUCING IMPROVED METAL OXIDE FINE PARTICLES, SURFACE-MODIFIED METAL OXIDE FINE PARTICLES, AND METAL OXIDE FINE PARTICLE DISPERSION LIQUID TOKYO OHKA KOGYO CO., LTD. (JP) 2020-05-07 US disclosed
US-9914687-B2 Composition containing vinyl-group-containing compound TOKYO OHKA KOGYO CO., LTD. (JP) 2018-03-13 US disclosed
US-9914687-B2 Composition containing vinyl-group-containing compound TOKYO OHKA KOGYO CO., LTD. (JP) 2018-03-13 US disclosed
US-20170275223-A1 TRANSPARENT BODY PRODUCTION METHOD, TRANSPARENT BODY, AND AMORPHOUS BODY TOKYO OHKA KOGYO CO., LTD. (JP) 2017-09-28 US disclosed
US-20170275223-A1 TRANSPARENT BODY PRODUCTION METHOD, TRANSPARENT BODY, AND AMORPHOUS BODY TOKYO OHKA KOGYO CO., LTD. (JP) 2017-09-28 US disclosed
EP-3199557-A1 TRANSPARENT BODY PRODUCTION METHOD, TRANSPARENT BODY, AND AMORPHOUS BODY Tokyo Ohka Kogyo Co., Ltd. (JP) 2017-08-02 EP disclosed
US-20160046552-A1 COMPOSITION CONTAINING VINYL-GROUP-CONTAINING COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2016-02-18 US disclosed
US-20160046552-A1 COMPOSITION CONTAINING VINYL-GROUP-CONTAINING COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2016-02-18 US disclosed
EP-2980058-A1 COMPOSITION CONTAINING VINYL-GROUP-CONTAINING COMPOUND Tokyo Ohka Kogyo Co., Ltd. (JP) 2016-02-03 EP disclosed
WO-2014157675-A1 COMPOSITION CONTAINING VINYL-GROUP-CONTAINING COMPOUND 東京応化工業株式会社 (JP) 2014-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160046552-A1 COMPOSITION CONTAINING VINYL-GROUP-CONTAINING COMPOUND C5, C1S, C1R ELANE 1905/4885ESR1 375/4885ESR2 1141/4885
US-20170275223-A1 TRANSPARENT BODY PRODUCTION METHOD, TRANSPARENT BODY, AND AMORPHOUS BODY IK, TTR, CUTA ELANE 3027/4885ESR1 1039/4885ESR2 2412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.