SCHEMBL161383

SCHEMBL161383

C=CN(C=C)C(=O)C(=C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 1/20 0.36
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2799435 0.78 TDP1 (0.36) ALDH1A1TDP1
SCHEMBL28663332 0.74 TDP1 (0.33) TDP1
SCHEMBL3124801 0.73
SCHEMBL8767089 0.70 TDP1 (0.42) ALDH1A1TDP1TSHR
SCHEMBL21626551 0.70 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL309028 0.69 TDP1 (0.44) ALDH1A1TDP1TSHR
SCHEMBL7203144 0.69 ALDH1A1 (0.41) ALDH1A1TDP1TP53TSHR
SCHEMBL28441938 0.69 ALDH1A1 (0.41) ALDH1A1TDP1TP53TSHR
SCHEMBL526286 0.67 TDP1 (0.42) ALDH1A1TDP1
SCHEMBL22921 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120095110-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2012-04-19 US claimed
US-20120095112-A1 BRANCHED POLYMER DISPERSANTS UNILEVER HOUSE (GB) 2012-04-19 US claimed
US-20120095111-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2012-04-19 US claimed
US-20120059069-A1 AMPHIPHILIC BRANCHED COPOLYMER, METHODS OF PREPARATION, EMULSIONS, AND USES UNILEVER PLC (GB) 2012-03-08 US claimed
EP-2424909-A1 AMPHIPHILIC BRANCHED COPOLYMER, METHODS OF PREPARATION, EMULSIONS, EMU AND USES Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2012-03-07 EP claimed
US-20160159940-A1 POLYDENDRONS The Univeristy of Liverpool (GB) 2016-06-09 US disclosed
US-20130345358-A1 USE OF BRANCHED ADDITION COPOLYMERS IN CURING SYSTEMS UNILEVER PLC (GB) 2013-12-26 US disclosed
US-20120178835-A1 USE OF BRANCHED ADDITION COPLYMERS IN FILMS AND MEMBRANES UNILEVER PLC (GB) 2012-07-12 US disclosed
US-20120157318-A1 Use of Branched Copolymers in Polymer Blends UNILEVER PLC (GB) 2012-06-21 US disclosed
US-20120095110-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2012-04-19 US disclosed
US-20120095112-A1 BRANCHED POLYMER DISPERSANTS UNILEVER HOUSE (GB) 2012-04-19 US disclosed
US-20120095111-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2012-04-19 US disclosed
EP-2424909-A1 AMPHIPHILIC BRANCHED COPOLYMER, METHODS OF PREPARATION, EMULSIONS, EMU AND USES Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2012-03-07 EP disclosed
EP-2102256-B1 POLYMERS UNILEVER PLC (GB) 2012-01-25 EP disclosed
US-20110172314-A1 AMPHIPHILIC BRANCHED POLYMERS AND THEIR USE AS EMULSIFIERS UNILEVER N.V. (NL) 2011-07-14 US disclosed
WO-2011033262-A1 USE OF BRANCHED ADDITION COPOLYMERS IN CURING SYSTEMS UNILEVER PLC (GB) 2011-03-24 WO disclosed
WO-2011033261-A1 USE OF BRANCHED ADDITION COPOLYMERS IN FILMS AND MEMBRANES UNILEVER PLC (GB) 2011-03-24 WO disclosed
WO-2011029580-A1 USE OF BRANCHED COPOLYMERS IN POLYMER BLENDS UNILEVER PLC (GB) 2011-03-17 WO disclosed
WO-2011029579-A2 USE OF POLYMERS UNILEVER PLC (GB) 2011-03-17 WO disclosed
EP-2285848-A1 AMPHIPHILIC BRANCHED POLYMERS AND THEIR USE AS EMULSIFIERS Unilever N.V. (NL) 2011-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159940-A1 POLYDENDRONS PARN, DSTN, DBN1 ALDH1A1 2419/4885TDP1 2579/4885TP53 2098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.