SCHEMBL526286

SCHEMBL526286

C=C(C)C(=O)N(O)C(=O)C(=C)C

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9846985 0.88 TDP1 (0.38) TDP1ALDH1A1
SCHEMBL11347329 0.80
SCHEMBL9847017 0.79 TDP1 (0.32) TDP1
SCHEMBL2452714 0.78
SCHEMBL9847010 0.77 ALDH1A1 (0.32) TDP1ALDH1A1
SCHEMBL309028 0.76 TDP1 (0.44) TDP1ALDH1A1HSD17B10LMNA
SCHEMBL22921 0.73
SCHEMBL10543953 0.73 TDP1 (0.42) TDP1ALDH1A1HSD17B10LMNA
SCHEMBL9820420 0.73 TDP1 (0.42) TDP1ALDH1A1HSD17B10LMNA
SCHEMBL278338 0.73 TDP1 (0.36) TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10034839-B2 Compositions and methods for delivery of kinase inhibiting peptides PURDUE RESEARCH FOUNDATION (US) 2018-07-31 US claimed
US-20170035702-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF KINASE INHIBITING PEPTIDES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-02-09 US claimed
US-9452218-B2 Compositions and methods for delivery of kinase inhibiting peptides PURDUE RESEARCH FOUNDATION (US) 2016-09-27 US claimed
EP-1263849-A1 DEGRADABLE CROSS-LINKING AGENTS AND CROSS-LINKED NETWORK POLYMERS FORMED THEREWITH Access Pharmaceuticals, Inc. (US) 2002-12-11 EP claimed
WO-2000078846-A1 DEGRADABLE CROSS-LINKING AGENTS AND CROSS-LINKED NETWORK POLYMERS FORMED THEREWITH ACCESS PHARMACEUTICALS, INC. (US) 2000-12-28 WO claimed
EP-0434438-B1 Hydrolytically degradable hydrophilic gels and the method for preparation thereof CESKE AKADEMIE VED (CZ) 1996-05-01 EP claimed
JP-4298504-A None JP disclosed
EP-4255965-A1 REACTIVE MICROPARTICLES AND THEIR USE TO PREPARE FUNCTIONAL HYDROGEL PARTICLES Allarta Life Science Inc. (CA) 2023-10-11 EP disclosed
WO-2022120478-A1 REACTIVE MICROPARTICLES AND THEIR USE TO PREPARE FUNCTIONAL HYDROGEL PARTICLES ALLARTA LIFE SCIENCE INC. (CA) 2022-06-16 WO disclosed
EP-2900783-A1 DEHYDRATED GEL COMPOSITIONS AND METHODS OF USING THE SAME Halliburton Energy Services, Inc. (US) 2015-08-05 EP disclosed
EP-2643372-A2 STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS Howard University (US) 2013-10-02 EP disclosed
EP-2643382-A2 BIODEGRADABLE STEALTH POLYMERIC PARTICLES FABRICATED USING THE MACROMONOMER APPROACH BY FREE RADICAL DISPERSION POLYMERIZATION Howard University (US) 2013-10-02 EP disclosed
EP-2598599-A1 STIMULI-RESPONSIVE HIGH VISCOSITY PILL Halliburton Energy Services, Inc. (US) 2013-06-05 EP disclosed
WO-2012071441-A2 BIODEGRADABLE STEALTH POLYMERIC PARTICLES FABRICATED USING THE MACROMONOMER APPROACH BY FREE RADICAL DISPERSION POLYMERIZATION HOWARD UNIVERSITY (US) 2012-05-31 WO disclosed
WO-2012071452-A2 STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS HOWARD UNIVERSITY (US) 2012-05-31 WO disclosed
WO-2012013934-A1 STIMULI-RESPONSIVE HIGH VISCOSITY PILL HALLIBURTON ENERGY SERVICES INC. (US) 2012-02-02 WO disclosed
WO-2003086316-A2 DEGRADABLE CROSSLINKERS, AND DEGRADABLE CROSSLINKED HYDROGELS COMPRISING THEM BIOSPHERE MEDICAL, INC. (US) 2003-10-23 WO disclosed
JP-H04298504-A HYDROLYTICALLY DEGRADABLE HYDROPHILIC GEL AND ITS PRODUCTION CESKOSLOVENSKA AKAD VED 1992-10-22 JP disclosed