Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.33 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16139025 | 0.94 | L3MBTL1 (0.42) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL16138868 | 0.94 | L3MBTL1 (0.42) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL16138624 | 0.92 | L3MBTL1 (0.45) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL16138810 | 0.92 | L3MBTL1 (0.41) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL16138805 | 0.92 | L3MBTL1 (0.41) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL16138869 | 0.92 | L3MBTL1 (0.43) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL16138906 | 0.92 | L3MBTL1 (0.43) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL15997147 | 0.92 | L3MBTL1 (0.43) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL21707003 | 0.92 | NR3C1 (0.32) | KDM4EATML3MBTL1JAK2JAK3 | |
| SCHEMBL20904289 | 0.91 | KDM4E (0.42) | KDM4EATML3MBTL1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9172045-B2 | 4-aminocarbazole compound and use thereof | TOSOH CORPORATION (JP) | 2015-10-27 | — | — | US | disclosed |
| US-9172045-B2 | 4-aminocarbazole compound and use thereof | TOSOH CORPORATION (JP) | 2015-10-27 | — | — | US | disclosed |
| US-20140296519-A1 | 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296519-A1 | 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |