Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16139097 | 0.99 | ALDH1A1 (0.38) | ALDH1A1RXFP1NPSR1RAB9AHTT | |
| SCHEMBL16139076 | 0.94 | ATM (0.35) | ALDH1A1RXFP1NPSR1RAB9AHTT | |
| SCHEMBL16138987 | 0.93 | KDM4E (0.36) | ALDH1A1ATMCYP1A2MAPTLMNA | |
| SCHEMBL16139099 | 0.93 | KDM4E (0.40) | ALDH1A1ATMCYP1A2MAPTLMNA | |
| SCHEMBL16139096 | 0.93 | ATM (0.38) | ALDH1A1ATMCYP1A2MAPTLMNA | |
| SCHEMBL16138779 | 0.91 | NPC1 (0.36) | ALDH1A1RXFP1NPSR1RAB9AHTT | |
| SCHEMBL16139120 | 0.91 | KDM4E (0.36) | ALDH1A1RXFP1NPSR1RAB9AATM | |
| SCHEMBL15997158 | 0.91 | KDM4E (0.38) | ALDH1A1RXFP1NPSR1RAB9AHTT | |
| SCHEMBL16138904 | 0.91 | KDM4E (0.38) | ALDH1A1RXFP1NPSR1RAB9AHTT | |
| SCHEMBL16139068 | 0.90 | NPC1 (0.38) | ALDH1A1RXFP1NPSR1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9172045-B2 | 4-aminocarbazole compound and use thereof | TOSOH CORPORATION (JP) | 2015-10-27 | — | — | US | disclosed |
| US-9172045-B2 | 4-aminocarbazole compound and use thereof | TOSOH CORPORATION (JP) | 2015-10-27 | — | — | US | disclosed |
| US-20140296519-A1 | 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296519-A1 | 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |