Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16139099 | 0.98 | KDM4E (0.40) | KDM4EATML3MBTL1MAPTPDE5A | |
| SCHEMBL16139096 | 0.98 | ATM (0.38) | KDM4EATML3MBTL1MAPTPDE5A | |
| SCHEMBL16139051 | 0.94 | KDM4E (0.34) | KDM4EATML3MBTL1MAPTPDE5A | |
| SCHEMBL16138985 | 0.93 | ALDH1A1 (0.37) | KDM4EATML3MBTL1MAPTPDE5A | |
| SCHEMBL16139073 | 0.93 | KDM4E (0.38) | KDM4EATML3MBTL1PDE5ALMNA | |
| SCHEMBL16138868 | 0.93 | L3MBTL1 (0.42) | KDM4EATML3MBTL1MAPTALDH1A1 | |
| SCHEMBL16139025 | 0.93 | L3MBTL1 (0.42) | KDM4EATML3MBTL1MAPTALDH1A1 | |
| SCHEMBL16139097 | 0.92 | ALDH1A1 (0.38) | KDM4EATML3MBTL1MAPTLMNA | |
| SCHEMBL16138721 | 0.92 | KDM4E (0.34) | KDM4EATML3MBTL1MAPTPDE5A | |
| SCHEMBL16138805 | 0.91 | L3MBTL1 (0.41) | KDM4EATML3MBTL1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9172045-B2 | 4-aminocarbazole compound and use thereof | TOSOH CORPORATION (JP) | 2015-10-27 | — | — | US | disclosed |
| US-9172045-B2 | 4-aminocarbazole compound and use thereof | TOSOH CORPORATION (JP) | 2015-10-27 | — | — | US | disclosed |
| US-20140296519-A1 | 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296519-A1 | 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |