Caprolactam

Caprolactam

SCHEMBL161418

C=C(C)C(N)=O.O=C1CCCCCN1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.57
FKBP5 Q13451 1/20 0.57
OR51E2 Q9H255 1/20 0.48
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 2/20 0.42
GAA P10253 1/20 0.42
POLB P06746 1/20 0.42
SIRT2 Q8IXJ6 6/20 0.37
SIRT1 Q96EB6 6/20 0.37
SIRT3 Q9NTG7 6/20 0.37
MERTK Q12866 1/20 0.33
CTSD P07339 3/20 0.32
CCR2 P41597 2/20 0.31
NNMT P40261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL1458792 0.93 OR51E2 (0.58) CRBNFKBP5OR51E2TDP1KDM4E
Caprolactam SCHEMBL1532933 0.89 CRBN (0.67) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL4163313 0.87 CRBN (0.59) CRBNFKBP5OR51E2KDM4EGAA
2-Pyrrolidone SCHEMBL7161774 0.85 OR51E2 (0.48) CRBNFKBP5OR51E2TDP1KDM4E
Caprolactam SCHEMBL13571212 0.85 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL8561273 0.85 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL11135219 0.85 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL16112032 0.83 CRBN (0.70) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL28170750 0.81 CRBN (0.52) CRBNFKBP5OR51E2KDM4EGAA
Acetic Acid SCHEMBL7696253 0.81 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10034818-B2 Use of a benefit delivery particle for malodour benefit CONOPCO, INC. (US) 2018-07-31 US disclosed
EP-3148650-B1 BENEFIT DELIVERY PARTICLE FOR TREATING SUBSTRATES UNILEVER PLC (GB) 2018-07-04 EP disclosed
WO-2018109469-A1 NOVEL PROCESS ITACONIX (U.K.) LIMITED (GB) 2018-06-21 WO disclosed
US-9993401-B2 Benefit delivery particle, process for preparing said particle, compositions comprising said particles and a method for treating substrates CONOPCO, INC. (US) 2018-06-12 US disclosed
EP-3148649-B1 USE OF PARTICLES TO ABSORB MALODORS UNILEVER PLC (GB) 2017-11-29 EP disclosed
US-20170202754-A1 BENEFIT DELIVERY PARTICLE FOR TREATING SUBSTRATES CONOPCO, INC., D/B/A UNILEVER (US) 2017-07-20 US disclosed
US-20170181935-A1 USE OF A BENEFIT DELIVERY PARTICLE FOR MALODOUR BENEFIT CONOPCO, INC., D/B/A UNILEVER (US) 2017-06-29 US disclosed
EP-3148650-A1 BENEFIT DELIVERY PARTICLE FOR TREATING SUBSTRATES Unilever PLC (GB) 2017-04-05 EP disclosed
EP-3148649-A1 USE OF A BENEFIT DELIVERY PARTICLE FOR MALODOUR BENEFIT Unilever PLC (GB) 2017-04-05 EP disclosed
WO-2015189625-A1 MATERIAL FUNCTIONALISED WITH A POLYMER IMPERIAL INNOVATIONS LIMITED (GB) 2015-12-17 WO disclosed
WO-2010149962-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2010-12-29 WO disclosed
WO-2010149957-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2010-12-29 WO disclosed
WO-2010149955-A1 BRANCHED POLYMER DISPERSANTS UNILEVER PLC (GB) 2010-12-29 WO disclosed
WO-2010125341-A1 AMPHIPHILIC BRANCHED COPOLYMER, METHODS OF PREPARATION, EMULSIONS, EMU AND USES UNILEVER PLC (GB) 2010-11-04 WO disclosed
US-20100144958-A1 POLYMERS UNILEVER PLC (GB) 2010-06-10 US disclosed
US-20100145001-A1 BRANCHED ORGANIC-INORGANIC POLYMERS UNILEVER PLC (GB) 2010-06-10 US disclosed
US-20100130641-A1 Polymers UNILEVER PLC (GB) 2010-05-27 US disclosed
WO-2010008667-A1 METHODS FOR MAKING ANTIMICROBIAL RESINS BAXTER INTERNATIONAL INC (US) 2010-01-21 WO disclosed
US-20090324666-A1 METHODS FOR MAKING ANTIMICROBIAL RESINS BAXTER INTERNATIONAL INC. (US) 2009-12-31 US disclosed
EP-2128180-A1 Amphiphilic branched polymers and their use as emulsifiers UNILEVER N.V. (NL) 2009-12-02 EP disclosed