Caprolactam

Caprolactam

SCHEMBL1532933

CC(N)=O.O=C1CCCCCN1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.67
FKBP5 Q13451 1/20 0.67
OR51E2 Q9H255 1/20 0.56
KDM4E B2RXH2 2/20 0.47
GAA P10253 1/20 0.47
POLB P06746 1/20 0.47
SIRT2 Q8IXJ6 7/20 0.40
SIRT1 Q96EB6 7/20 0.40
SIRT3 Q9NTG7 7/20 0.40
MERTK Q12866 1/20 0.35
CCR2 P41597 2/20 0.34
CTSD P07339 3/20 0.34
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Caprolactam SCHEMBL13571212 0.91 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
2-Pyrrolidone SCHEMBL3729403 0.91 OR51E2 (0.68) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL11135219 0.91 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL8561273 0.91 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL16112032 0.89 CRBN (0.70) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL161418 0.89 CRBN (0.57) CRBNFKBP5OR51E2KDM4EGAA
Acetic Acid SCHEMBL7696253 0.87 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL10710154 0.87 CRBN (0.80) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL28464885 0.87 CRBN (0.80) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL28250859 0.85 CRBN (0.70) CRBNFKBP5OR51E2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106749805-B A kind of atom transfer radical polymerization method acted on using low temperature eutectic 华中科技大学 2019-07-09 CN claimed
CN-106749805-A A kind of atom transfer radical polymerization method of utilization low temperature eutectic effect 华中科技大学 2017-05-31 CN claimed
CN-106749805-B A kind of atom transfer radical polymerization method acted on using low temperature eutectic 华中科技大学 2019-07-09 CN disclosed
CN-109963896-A Method and apparatus for continuously producing aromatic cyclic oligomer, and method for producing aromatic polymer 株式会社吴羽 2019-07-02 CN disclosed
CN-106749805-A A kind of atom transfer radical polymerization method of utilization low temperature eutectic effect 华中科技大学 2017-05-31 CN disclosed
EP-2293670-B1 COMPOSITIONS AND METHODS FOR NAIL FUNGUS TREATMENT ARCH CHEM INC (US) 2016-03-30 EP disclosed
EP-2293670-A1 COMPOSITIONS AND METHODS FOR NAIL FUNGUS TREATMENT Arch Chemicals, Inc. (US) 2011-03-16 EP disclosed
WO-2010144293-A1 SYNTHESIS OF TELCAGEPANT AND INTERMEDIATES THEREOF MERCK SHARP & DOHME CORP. (US) 2010-12-16 WO disclosed
WO-2009148794-A1 COMPOSITIONS AND METHODS FOR NAIL FUNGUS TREATMENT ARCH CHEMICALS, INC. (US) 2009-12-10 WO disclosed
US-20090298805-A1 TOPICAL PYRITHIONE COMPOSITIONS AND METHODS FOR TREATMENT OF NAIL FUNGUS ARCH CHEMICALS, INC. 2009-12-03 US disclosed