Caprolactam

Caprolactam

SCHEMBL8561273

NC(N)=O.O=C1CCCCCN1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.73
FKBP5 Q13451 1/20 0.73
OR51E2 Q9H255 1/20 0.61
KDM4E B2RXH2 2/20 0.50
GAA P10253 1/20 0.50
POLB P06746 1/20 0.50
MERTK Q12866 1/20 0.36
SIRT2 Q8IXJ6 3/20 0.36
SIRT1 Q96EB6 3/20 0.36
SIRT3 Q9NTG7 3/20 0.36
CCR2 P41597 2/20 0.33
CTSD P07339 3/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Caprolactam SCHEMBL13571212 1.00 CRBN (0.73) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL1532933 0.91 CRBN (0.67) CRBNFKBP5OR51E2KDM4EGAA
2-Pyrrolidone SCHEMBL6849688 0.91 OR51E2 (0.75) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL28464885 0.91 CRBN (0.80) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL28250859 0.89 CRBN (0.70) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL28258453 0.88 CRBN (0.76) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL4961789 0.88 CRBN (0.76) CRBNFKBP5OR51E2KDM4EGAA
Caprolactam SCHEMBL28301539 0.88 CRBN (0.84) CRBNFKBP5OR51E2KDM4EGAA
SCHEMBL20589476 0.88 CRBN (0.94) CRBNFKBP5OR51E2KDM4EGAA
SCHEMBL20670735 0.88 CRBN (0.94) CRBNFKBP5OR51E2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830421-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1998-03-25 EP claimed
US-5665852-A USEFUL IN POWDER COATING COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 1997-09-09 US claimed
WO-1996040825-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO claimed
CN-102766259-B Compositions for anionic polymerization of lactam 布吕格曼化工L.布吕格曼两合公司 2016-10-19 CN disclosed
CN-102766259-A Composition for anionic lactam polymerization BRUEGGEMANNCHEMICAL L BRUEGGEMANN KG 2012-11-07 CN disclosed
EP-0830421-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1998-03-25 EP disclosed
US-5665852-A USEFUL IN POWDER COATING COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 1997-09-09 US disclosed
WO-1996040825-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO disclosed
US-5527797-A IONTOPHORESIS MACROCHEM CORPORATION (US) 1996-06-18 US disclosed