SCHEMBL161425

SCHEMBL161425

C=Cc1ccc(CSC(=S)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
IDO1 P14902 4/20 0.37
NOS1 P29475 2/20 0.37
NOS3 P29474 1/20 0.37
NOS2 P35228 1/20 0.37
HDAC2 Q92769 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2045957 0.94 CA12 (0.46) CA1CA2CA12CA9ALDH1A1
SCHEMBL1524417 0.86 CA12 (0.53) CA1CA2CA12CA9IDO1
SCHEMBL15669273 0.84 CA12 (0.42) CA1CA2CA12CA9ALDH1A1
SCHEMBL164262 0.83 CA12 (0.39) CA1CA2CA12CA9ALDH1A1
SCHEMBL36459 0.82 CA12 (0.59) CA1CA2CA12CA9IDO1
SCHEMBL19148629 0.79 ALDH1A1 (0.44) CA1CA2CA12CA9ALDH1A1
SCHEMBL164241 0.79 CA12 (0.59) CA1CA2CA12CA9IDO1
SCHEMBL29060727 0.78 L3MBTL1 (0.54) CA1CA2CA12CA9ALDH1A1
SCHEMBL31444180 0.77 CYP2D6 (0.33) CA1CA2CA12CA9ALDH1A1
SCHEMBL13991169 0.77 HPGD (0.49) CA1CA2CA12CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747339-A1 INDUSTRIAL GEAR LUBRICANT The Lubrizol Corporation (US) 2026-05-27 EP disclosed
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition DENKA COMPANY LIMITED (JP) 2026-05-12 US disclosed
EP-2292668-B2 Process for preparing polymers and compositions thereof LUBRIZOL CORP (US) 2025-09-10 EP disclosed
US-20250269096-A1 FLUOROPOLYMER MEDICAL DEVICES UNOMEDICAL AS (DK) 2025-08-28 US disclosed
EP-4583933-A1 FLUOROPOLYMER MEDICAL DEVICES Unomedical A/S (DK) 2025-07-16 EP disclosed
EP-4583934-A1 MEDICAL DEVICES Unomedical A/S (DK) 2025-07-16 EP disclosed
US-20250195832-A1 MEDICAL DEVICES UNOMEDICAL AS (DK) 2025-06-19 US disclosed
CN-115348982-B Chloroprene block copolymer, latex composition, and rubber composition 电化株式会社 2025-05-30 CN disclosed
WO-2025019655-A1 INDUSTRIAL GEAR LUBRICANT THE LUBRIZOL CORPORATION (US) 2025-01-23 WO disclosed
EP-4223837-B1 RUBBER COMPOSITION, VULCANIZED PRODUCT, AND VULCANIZED MOLDED ARTICLE DENKA COMPANY LTD (JP) 2024-12-25 EP disclosed
US-20070244018-A1 Star Polymers and Compositions Thereof THE LUBRIZOL CORPORATION 2007-10-18 US disclosed
EP-1833852-A1 PROCESS FOR PREPARING POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2007-09-19 EP disclosed
EP-1833868-A2 STAR POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2007-09-19 EP disclosed
US-7250479-B2 Polymerization with living characteristics E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-31 US disclosed
WO-2006047398-A2 STAR POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2006-05-04 WO disclosed
WO-2006047393-A1 PROCESS FOR PREPARING POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2006-05-04 WO disclosed
US-20040171777-A1 Polymerization with living characteristics COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-09-02 US disclosed
EP-0910587-B1 POLYMERIZATION WITH LIVING CHARACTERISTICS DU PONT (US) 2001-12-12 EP disclosed
EP-0910587-A1 POLYMERIZATION WITH LIVING CHARACTERISTICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-28 EP disclosed
WO-1998001478-A1 POLYMERIZATION WITH LIVING CHARACTERISTICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition ALG3, VCL, DNMT1 CA1 315/4885CA2 982/4885CA12 1062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.