Isoleucine

Isoleucine

SCHEMBL1614385

CC[C@H](C)[C@H](N)C(=O)O.O=P(O)(O)CP(=O)(O)O.O=P(O)(O)CP(=O)(O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.46
LAP3 P28838 3/20 0.43
GLUL P15104 1/20 0.42
METAP1 P53582 1/20 0.41
DPP4 P27487 1/20 0.40
DPP8 Q6V1X1 1/20 0.40
DPP9 Q86TI2 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MMP2 P08253 1/20 0.39
THRB P10828 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 1/20 0.38
GCLC P48506 1/20 0.38
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoleucine SCHEMBL31276087 0.90 SLC7A5 (0.46) SLC7A5LAP3METAP1DPP4DPP8
Isoleucine SCHEMBL1255583 0.85 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9ALDH1A1
Isoleucine SCHEMBL5973421 0.85 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9ALDH1A1
Isoleucine SCHEMBL2783498 0.85 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9ALDH1A1
Isoleucine SCHEMBL8186739 0.85 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9ALDH1A1
Isoleucine SCHEMBL8045737 0.85 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9ALDH1A1
Isoleucine SCHEMBL8868 0.85
Isoleucine SCHEMBL1147268 0.85 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9ALDH1A1
Isoleucine SCHEMBL8043620 0.85 SLC7A5 (0.55) SLC7A5DPP4DPP8DPP9ALDH1A1
Isoleucine SCHEMBL20340795 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178792-B1 METHOD OF SCALE INHIBITION ITALMATCH CHEMICALS SPA (IT) 2021-04-14 EP disclosed
EP-3178792-A1 METHOD OF SCALE INHIBITION Italmatch Chemicals S.P.A. (IT) 2017-06-14 EP disclosed
US-9108866-B2 Method of scale inhibition ITALMATCH CHEMICALS SPA (IT) 2015-08-18 US disclosed
US-20130264289-A1 METHOD OF SCALE INHIBITION ITALMATCH CHEMICALS SPA (IT) 2013-10-10 US disclosed
US-8551931-B2 Surface treatment composition containing phosphonic acid compounds DEQUEST AG (CH) 2013-10-08 US disclosed
US-8505626-B2 α-Amino acid phosphonic acid compounds, method of preparation of use thereof DEQUEST AG (CH) 2013-08-13 US disclosed
US-8461088-B2 Method of scale inhibition DEQUEST AG (CH) 2013-06-11 US disclosed
EP-2252679-B1 SURFACE TREATMENT COMPOSITION CONTAINING PHOSPHONIC ACID COMPOUNDS DEQUEST AG (CH) 2013-04-17 EP disclosed
EP-2054423-B1 ALPHA-AMINO ACID PHOSPHONIC ACID COMPOUNDS, METHOD OF PREPARATION AND USE THEREOF DEQUEST AG (CH) 2012-07-18 EP disclosed
US-20110124533-A1 METHOD OF SCALE INHIBITION DEQUEST AG 2011-05-26 US disclosed
US-20110086791-A1 SURFACE TREATMENT COMPOSITION CONTAINING PHOSPHONIC ACID COMPOUNDS DEQUEST AG (CH) 2011-04-14 US disclosed
US-20100186961-A1 ALPHA AMINO ACID PHOSPHONIC ACID COMPOUNDS, METHOD OF PREPARATION OF USE THEREOF THERMPHOS TRADING GMBH 2010-07-29 US disclosed
EP-2090646-A1 Surface treatment composition containing phosphonic acid compounds Thermphos Trading GmbH (CH) 2009-08-19 EP disclosed
EP-1886976-A1 Method of scale inhibition Thermphos Trading GmbH (CH) 2008-02-13 EP disclosed
EP-1887011-A1 Alpha amino acid phosphonic acid compounds, method of preparation and use thereof Thermphos Trading GmbH (CH) 2008-02-13 EP disclosed