Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 12/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | F9 | P00740 | 6/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995005 | 0.80 | MAP4K4 (0.41) | F11KLK1MAP4K4 | |
| SCHEMBL30994989 | 0.80 | F11 (0.41) | F11KLK1F9 | |
| SCHEMBL29227912 | 0.80 | MAP4K4 (0.41) | F11KLK1MAP4K4 | |
| SCHEMBL28653879 | 0.79 | F11 (0.42) | F11KLK1F9 | |
| SCHEMBL29396971 | 0.79 | F11 (0.42) | F11KLK1F9 | |
| SCHEMBL30995057 | 0.78 | F11 (0.42) | F11KLK1F9 | |
| SCHEMBL29227955 | 0.78 | F11 (0.42) | F11KLK1F9 | |
| SCHEMBL30995006 | 0.76 | ALDH1A1 (0.49) | F11KLK1F9 | |
| SCHEMBL29062100 | 0.75 | F11 (0.52) | F11 | |
| SCHEMBL30408842 | 0.75 | F11 (0.52) | F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014160592-A2 | FACTOR XIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-10-02 | — | — | WO | disclosed |